Epidemiological characteristics of high-risk human papillomavirus infection during pregnancy and the correlation between the high-risk human papillomavirus infection and the pregnancy outcomes

doi:10.3969/j.issn.1006-7795.2018.06.009

Abstract

Abstract: Objective To investigate the epidemiological characteristics of high-risk human papillomavirus(HR-HPV) in pregnant women during pregnancy and its effect on pregnancy outcomes. Methods From March 2013 to December 2017, a total of 3 967 pregnant women who established maternal health records and received HR-HPV examinations,1:3 paired non-pregnant women of the same age and the same period,were selected to investigate the epidemiological characteristics of HR-HPV infection during pregnancy by parallel controlled study, and to investigate the impact of HR-HPV infection on pregnancy outcome by Cohort study. Results The total infection rate, multiple mixed infection and high viral load of HR-HPV in pregnant women were lower than those in non-pregnant women (P<0.05). There was no significant correlation between the HR-HPV infection rate and age in pregnant women.For pregnant women with HR-HPV infection,the incidence of oligohydramnios increased while the incidence of acute labor decreased, and the differences were statistically significant (P<0.05). Conclusion HR-HPV infection during the pregnancy does not increase the risk of other adverse pregnancy outcomes except for oligohydramnios. The rate and severity of HR-HPV infection in the pregnancy women were lower than that in non-pregnancy women, which is inconsistent with most international data. It may be related to the significant decline in the sexual activities frequency of Chinese pregnant women.

Key words: high-risk human papillomavirus, pregnancy, epidemiology, pregnancy outcome

CLC Number:

R714.25

Huang Wenyang, He Xin, Li Weihua, Zhang Xuefang, Li Zhan, Gu Li, Lu Junli, Wang Shuzhen. Epidemiological characteristics of high-risk human papillomavirus infection during pregnancy and the correlation between the high-risk human papillomavirus infection and the pregnancy outcomes[J]. Journal of Capital Medical University, 2018, 39(6): 836-840.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2018.06.009

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2018/V39/I6/836

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