Journal of Capital Medical University ›› 2021, Vol. 42 ›› Issue (2): 200-203.doi: 10.3969/j.issn.1006-7795.2021.02.006

• Clinical Study on Obstetrics and Gynecology • Previous Articles     Next Articles

Effects of minimally invasive bariatric surgery on menstrual cycle and reproductive function in severely obese women

Li Jian1#, Wu Fengyun1#, Zhang Nengwei2, Lian Dongbo2, Fan Qing2, Xu Guangzhong2, Du Dexiao2, Sun Zhipeng2, Du Yanmin2, Bai Wenpei1, *   

  1. 1. Department of Obstetrics and Gynecology, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China;
    2. Department of Bariatric Surgery, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China
  • Received:2021-02-22 Published:2021-04-26
  • Contact: *E-mail:baiwp@bjsjth.cn
  • Supported by:
    This study was supported by Beijing Hospitals Authority “Ascent” Plan(DFL20190701),Open Research Project of Key Laboratory of Capital Medical University (2018-KF09).

Abstract: Objective To evaluated the impact of minimally invasive bariatric surgery on menstrual cycle and fertility of severely obese women.Methods A total of 55 obese women who underwent minimally invasive bariatric surgery in our hospital from 2015 to 2019 were enrolled. The information of menstrual cycle, weight, pregnancy at 1, 3, 6 and 12 months after surgery were followed up, and those with fertility requirements were followed up to the end of delivery. The differences of weight, menstrual cycle and pregnancy rate before and after operation were compared. Results At baseline, the average age was (27.82±5.16) years old, the average body mass index (BMI) was (39.42±7.39) kg/m2, and the average body weight was (108.85±20.84) kg. The rate of menstrual disorder was 70.91%(39/55). The rate of sleeve gastrectomy and gastric bypass was 87.27% and 12.73%, respectively. The median follow-up time was 35(13-67) months. The most obvious weight loss occurred in the first month after surgery, with an average weight loss of (11.21±5.16) kg (-10.18%). At 6 months and one year after surgery, the average weight loss were (29.79±10.28) kg (-26.94%) and (34.15±12.72) kg (-30.56%) respectively, and the BMI dropped to (27.09±4.25) kg/m2 one year after surgery. The improvement rate of menstrual disorder was 71.79%(28/39). The median time of menstruation recovery was 1.5(0.5-8.0)months after operation, and the overall menstrual disorder rate decreased to 20%(11/55). The improvement rate of infertility was 54.17% (13/24). The average time of pregnancy and delivery after operation was (24.06±14.91) months and (33.21±15.17) months, respectively, and the average birth weight was (2.89±1.68) kg. Conclusion Minimally invasive bariatric surgery significantly improved the menstrual cycle and pregnancy rate of women with severe obesity. Pregnancy within two years after minimally invasive surgery did not affect the weight of the newborn.

Key words: minimally invasive bariatric surgery, obesity, menstrual disorder, pregnancy

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