Journal of Capital Medical University ›› 2018, Vol. 39 ›› Issue (2): 286-291.doi: 10.3969/j.issn.1006-7795.2018.02.024

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Analysis of etiology and clinical features of chronic pancreatitis in the elderly

Chi Tianyu, Zhang Mei   

  1. Department of Gastroenterology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China
  • Received:2017-07-16 Online:2018-03-21 Published:2018-04-14

Abstract: Objective To investigate the etiology and clinical features of 106 elderly cases of chronic pancreatitis in Beijing. Methods Retrospective analysis of 106 elderly patients with diagnosis and treatment of chronic pancreatitis within 10 years in Xuanwu Hospital of Capital Medical University (January 2007 to January 2017), was compared with 132 cases of non-elderly patients with chronic pancreatitis in the same period. We compared the gender, etiology, clinical manifestations, complications and imaging diagnosis between two groups. Results The average age was (65.3±4.7) years old and male:female was 1.72:1 in 106 elderly patients. In the etiology analysis of elderly chronic pancreatitis, the biliary tract diseases accounted for 47.28%, followed by alcoholism 21.70%, which was the main cause in non-elderly people with chronic pancreatitis. The main clinical manifestations of chronic pancreatitis in the elderly were abdominal pain (64.15%) and abdominal distension (33.96%), which were significantly different from those of non-elderly patients with chronic pancreatitis. The complications of chronic pancreatitis in elderly patients were similar to those in non-elderly. The elderly group, image detection positive rate from high to low occurred in the order of endoscopic retrograde cholangiopancreatography (ERCP), endoscopicultrasound (EUS), magnetic resonance imaging (MRI)/magnetic resonancecholangiopancreatography (MRCP),computed tomography (CT) and ultrasound. Different image detection methods had significant difference both in the elderly group and non-elderly group. However there was no difference between the two groups for the same image method. Conclusion The main causes of chronic pancreatitis in the elderly were biliary diseases and alcohol abuse. The clinical manifestations were abdominal pain and abdominal distension, and the diagnosis should be based on the specific conditions of the elderly patients, and choose safe and high diagnostic imaging methods.

Key words: elderly, chronic pancreatitis, etiology analysis, clinical characteristics

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