Abstract: The standard sex-linked recessive lethal test was used to test whether compounds induce lethal mutations in male germ cells of Drosophila. The present paper deals with study on the mutagenic potontial of SF-Xiaoxiling in Drosophila. The Drosophila melanogaster stocksused were the Oregon K males wild type and Base females. Oregon K males. Iday old were treaed with test agenis and maied to Base virgin females, 2～4 days old. Statistical significance tests were based on the tables of Kastenbaum and Bowman. The results showed that no significant enhancement of mutation frequency was observed when flies were fed on SF-Xiaoxiling 4g/L, 6g/L and 8g/L selution. This study shows that SF-Xiaoxiling is without mutagenicity.

Key words: SF-Xiaoxiling, Drosophila melanogaster, mutation, sex-linked recessive lethal test(SLRL test)