Clinical Effects of Nifedipine on Blood Pressure and Left Ventricular Performance in Patients with Hypertension without Complication

Abstract

Abstract: 10 patients with hypertension without complication were treated with 10 mg of nifedipine (Chinese product) three times a day.It was found that on 3rd and 7th days the blood pressure decreased on the average from 161.4/92.8 to 139.8/84.6 and 134.2/84.6 mmHg respectively;mean arterial blood pressure decreased on the average from 114.2 to 104.2 and 102.0 mmHg;total peripheral resistance decreased on the average from 1741 to 1514 and 1263 dyn·s/cm⁵ respectively.With echocardiography we found that early diastolic time-velocity integral increased on the average from 7.2 to 8.4 and 8.7 at third and seventh day.Early diastolic and atrial contraction peak flow velocity and cardiac index were also improved.From above-mentioned findings we are of the opinion that Nifedipine (produced in China) is effective in reducing blood pressure and improving left ventricular performance.

Key words: hypertension, Nifedipine, heart function tests, echocardiography

Hua Qi;Wang Jiarui;Shi Shuying;Hong Fangyu;Tang Zhe. Clinical Effects of Nifedipine on Blood Pressure and Left Ventricular Performance in Patients with Hypertension without Complication[J]. Journal of Capital Medical University, 1991, 12(3): 215-217.

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Clinical Effects of Nifedipine on Blood Pressure and Left Ventricular Performance in Patients with Hypertension without Complication

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