Abstract: The study eavluated the effect on bone and lipoid metabolism in women of reproductive age undergoing unilateral ovariotomy. A postoperative follow-up study was performed in 21 cases for three years after operation and twenty normal women were enrolled in control group. There was no significant difference in bone density, biochemical markers of bone metabolism or the levels of plasma E₂, and FSH between two the groups. However, the concentration of plasma T was markedly higher in the study group. And TC and apoB levels were higher in the study group. It seems there is no effect on bone metabolism in women with unilateral ovarotomy. After operation, lipoid metabolism is changed.

Key words: ovariectomy, estrogen, bone metabolism, lipoid metabolism