Journal of Capital Medical University ›› 2013, Vol. 34 ›› Issue (4): 530-534.doi: 10.3969/j.issn.1006-7795.2013.04.010

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Physiological significance of estrogen

SHI Yuhua1, CHEN Zijiang2   

  1. 1. Reproductive Medical Hospital, Shandong University, Jinan 250001, China;
    2. Provincial Hospital, Shandong University, Jinan 250001, China
  • Received:2013-06-10 Online:2013-08-21 Published:2013-07-20
  • Supported by:

    This study was supported by the National Basic Research Program of China(2011CB944502), National Key Technology Research and Development Program of China(2012BAI32B04), and the National Natural Science Foundation of China(81070461).

Abstract:

Female reproductive endocrinology system plays an important role in the growth and development of other systems and the reproduction of human being. Estrogen is the most important steroid sex hormone in women, which exert its impact via specific intranuclear receptors in target cells. Estrogen plays an irreplaceable role in every life phase of human being. Estrogen promotes the development of secondary sexual characteristics and reproductive system in puberty, while it maintains menstrual cycle and female characters, facilitate embryo implantation and cause maternal changes during pregnancy in child-bearing period. Besides reproductive system, estrogen also impact skeletal system, central nervous system and cardiovascular system. Due to the low level of estrogen, urogenital system becomes atrophic and meanwhile the risk of osteoporosis, cardiovascular disease and senile dementia increases in postmenopausal women.

Key words: estrogen, physiology, reproductive system, puberty, menopause

CLC Number: