Abstract: Objective To investigate the hemodynamic changes of the pregnancy failure by Doppler ultrasound.Methods 273 cases were examined with ultrasound, there were 156 cases of normal early pregnancy, 52 cases pregnancy failure and 65 cases anembryonic pregnancy. The bilateral arteries of uterus and ovary were measured by trans abdominal color and pulsed Doppler. The data of the blood flow were analysed by statistically.Results The measurement of the pulse index(PI), the resistant index(RI) and the ratio between the peak of systolic velocity and the end of diastolic velocity(S/D) of dominant and non-dominant uterus artery in pregnancy failure were much lower than that of normal early pregnancy. There was significant statistic difference in the PI, RI and S/D between them. And there were similar ities between the pregnancy failure and anembryonic pregnancy, with no statistic difference between them. No significant difference was found between the pregnancy failure and normal early pregnancy in terms of ovarial artery measurement.Conclusion The change of PI and RI in uterus artery could be used to evaluate the outcome of the pregnancy. When the PI and RI of the dominant uterus artery are lower than 1.80 and 0.77 respectively, the risk of the pragnancy failure is higher than normal.

Key words: ultrasonography, hemodynamics, pregnancy failure