Abstract: Objective To investigate the efficacy and safety of laser peripheral iridoplasty combined with iridotomy for acute angle-closure glaucoma.Methods Twenty-six patients with acute primary angle-closure glaucoma(PACG)were recruited into the study.Each patient received the following IOP-lowering drugs: 1% pilocarpine,topical β-blocker,acetazolamide,mannitol.The IOP of each patient were controlled below 22 mmHg(1 mmHg=0.133 kPa).Then 26 cases(26 eyes) underwent laser peripheral iridoplasty at the iris root in all 360 degrees and had 30 laser spots.Then all cases were treated by laser iridotomy using Nd:YAG laser.Results Two hours after laser treatment,the intraocular pressure(IOP) was ≤21 mmHg and angle of anterior chamber opened again in all cases.Conclusion Laser peripheral iridoplasty combined with iridotomy can effectively reopen the closed anterior chamber angle and relieve pupil block in PACG patients who are experiencing acute attacks.

Key words: acute angle-closure glaucoma, laser, iridoplasty, iridotomy