Abstract:

Objective To observe the relationship between high-sensitivity C-reactive protein and severity of coronary artery lesions in unstable angina patients. Methods Totally 1 528 patients(954 males and 574 females) with unstable angina pectoris seen in our hospital were enrolled into this study. High-sensitivity C-reactive protein(CRP) levels were measured in all patients. Coronary angiography was performed in every patient, and the severity of coronary stenosis was evaluated by using the Gensini scoring system. The patients were divided into three groups which were mild, moderate and severe, according to the Gensini score. The data were analyzed by SPSS software. We studied the relationship between high-sensitivity C-reactive protein and severity of coronary artery lesions in unstable angina patients.Results The CRP levels were significantly correlated with the severity of coronary stenosis(P<0.01). Conclusion The high-sensitivity CRP levels might be an important risk factor related with the severity of coronary stenosis.

Key words: unstable angina pectoris, high-sensitivity C-reactive protein, coronary angiography