Diagnostic value of ischemia severity at myocardial perfusion imaging in elderly persons with suspected coronary disease

doi:10.3969/j.issn.1006-7795.2021.01.005

Abstract

Abstract: Objective To evaluate the value of different thresholds of myocardial perfusion and ischemia scores obtained from myocardial perfusion imaging (MPI) in diagnosing in elderly persons with suspected coronary artery disease. Methods A total of 99 patients [mean age (67.24±5.18) years, 53 male and 46 female] who underwent two-day rest-stress MPI in Department of Nuclear Medicine, Civil Aviation General Hospital from August 2017 to June 2020 were enrolled, and the data were analyzed retrospectively. According to coronary angiography (CAG) results, the patients undergoing CAG within 6 months were divided into coronary artery disease (CAD) group(patients group, 52 cases) and non-CAD group (control group, 47 cases). The general clinical information, summed rest score (SRS), summed stress score (SSS) and summed difference score (SDS) were collected. t test and χ² test were used to compare the data between the different groups. Multivariate Logistic regressions were used to establish the independent diagnostic value and accuracy of MPI parameters. Results In multivariate analysis accounting for clinical variables associated with CAD, both SSS (7.425, 95%CI: 2.873-19.192, P＜0.001) and SDS (8.020, 95%CI: 2.980-21.984, P＜0.001) were independently related with CAD. The consistency of SSS＞3 in the diagnosis of CAD is better than the different threshold of myocardial perfusion combined with ischemia. Conclusion The myocardial perfusion and ischemia scores from MPI are independent risk factors for predicting CAD in the elderly persons, but SSS combined with different SDS thresholds could not improve the diagnostic efficiency of elderly persons with suspected coronary disease.

Key words: coronary artery disease, myocardial perfusion imaging, myocardial ischemia

CLC Number:

Gu Shanshan, Lu Jie, Chen Gang. Diagnostic value of ischemia severity at myocardial perfusion imaging in elderly persons with suspected coronary disease[J]. Journal of Capital Medical University, 2021, 42(1): 26-30.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2021.01.005

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2021/V42/I1/26

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