Journal of Capital Medical University ›› 2025, Vol. 46 ›› Issue (3): 496-502.doi: 10.3969/j.issn.1006-7795.2025.03.014

Previous Articles     Next Articles

Research progress of cognitive function decline in patients with coronary heart disease

Huo Bixiu1,2,  Jia Hongxiao1,2* , Ning Yanzhe1,2   

  1. 1. Beijing Key Laboratory of Mental Disorders, National Clinical Research Center for Mental Disorders & National Center for Mental Disorders Beijing Anding Hospital, Capital Medical University,Beijing 100088,China; 2. Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing 100069,China
  • Received:2025-03-04 Online:2025-06-21 Published:2025-06-25
  • Supported by:
    This study was supported by National Natural Science Foundation of China (82174311), Beijing Traditional Chinese Medicine Inheritance “ New 3+3” Program Demonstration Case Project (2023-ZYSF-19), Sanming Project of Medicine in Shenzhen(SZZYSM202411001).

Abstract: Coronary heart disease (CHD) imposes a high  disease burden in China and it is still increasing significantly. There is a two-way connection between the heart and the brain, and the premature and rapid decline of cognitive function in patients with CHD has attracted increasing interesting from researchers, but clinical professionals often pay more attention to heart-related symptoms and ignore the impact of cognitive function decline on the quality of life of patients with CHD. This article reviews the current research progresses of cognitive decline in CHD patients from the aspects of manifestation, influencing factors, pathological mechanism and intervention measures. It offers a reference for medical professionals to understand this problem more deeply.

Key words: coronary heart disease, cognitive function, heart-brain connection, pathological mechanism, research progress

CLC Number: