Effect of microglia in alcohol-induced brain damage

doi:10.3969/j.issn.1006-7795.2014.03.012

Abstract

Abstract:

Alcohol has a significant effect on the central nervous system, as the key immune effector cells in the brain, some studies proved that microglia plays an important role in the neurotoxicity of alcohol, which can lead to neuronal death and degeneration. Some investigations demonstrated that microglia is beneficial to maintain a steady state rather than causing nerve degeneration, microglia activation is the end of the damage induced by the alcohol rather than cause. This paper reviews the microglial response and related mechanism in neuronal death and degeneration caused by alcohol.

Key words: alcoholic brain damage, microglia, inflammation response, in vivo, in vitro

CLC Number:

Li Jincheng, Zhao Haiping, Luo Yumin. Effect of microglia in alcohol-induced brain damage[J]. Journal of Capital Medical University, 2014, 35(3): 320-323.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2014.03.012

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2014/V35/I3/320

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