Journal of Capital Medical University ›› 2016, Vol. 37 ›› Issue (1): 30-33.doi: 10.3969/j.issn.1006-7795.2016.01.006

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Risk and early warning factors in the nonalcoholic fatty liver disease patients

Wang Canghai1,2, Su Hui1,2, Tao Xuguang3, Lin Xiangchun1,2, Wu Jing1,2, Tai Weiping1,2, Liu Kuiliang1,2   

  1. 1. Department of Gastroenterology, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China;
    2. Faculty of Gastroenterology of Capital Medical University, Beijing 100050, China;
    3. Institute of Basic Theory for Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing 100000, China
  • Received:2015-12-25 Online:2016-02-21 Published:2016-02-01
  • Supported by:
    This study was supported by National Center for Clinical Medical Research of Digestive System Diseases(2015BAI13B09).

Abstract: Objective To investigate the risk factors for the nonalcoholic fatty liver disease(NAFLD) patients in railway staffs. Methods We measured the waist, height, and detected the serum fasting blood glucose, blood lipids, liver function, renal function and blood routine.Serum interleukin-6(IL-6), tumor necrosis factor-α(TNF-α) were detected using the method of liquid phase chip. Result Logistic regression analysis showed that the incidence and the seriousness of NAFLD were associated with higher body mass index(BMI), triglyceride, waist circumference and blood glucose. Serum IL-6, TNF-α were higher in patients with different severity of nonalcoholic fatty liver disease, especially in family members of patients iwth NAFLD. Conclusion The seriousness of NAFLD was associated with the level of metabolic disorders.IL-6 and TNF-α were much higher in family members of patients with NAFLD.

Key words: nonalcoholic fatty liver disease, risk factors, interleukin-6, tumor necrosis factor-α

CLC Number: