Journal of Capital Medical University ›› 2018, Vol. 39 ›› Issue (6): 928-932.doi: 10.3969/j.issn.1006-7795.2018.06.023

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Meta-analysis of the effect of the correction of deviation of the nasal septum in patients with allergic rhinitis

Xu Qingqing1, Duan Su1, Wang Xiangdong2,3, Zhang Luo2,3   

  1. 1. Department of Allergy, Beijing Tongren Hospital, Capital Medical University, Beijing 100176, China;
    2. Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China;
    3. Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing 100005, China
  • Received:2018-04-24 Online:2018-11-21 Published:2018-12-19
  • Supported by:
    This study was supported by National Natural Science Foundation of China (81370436).

Abstract: Objective To evaluate the treatment effect of endoscopic nasal septum surgery on perennial allergic rhinitis patients with nasal septum deviation by the method of Meta analysis. Methods Allergic rhinitis on endoscopic nasal septum surgery treatment with nasal septum deviation the Cochrane searched PubMed database, The Cochrance Library database, VIP Database for Chinese Technical Periodicals, Wanfang database, China National Knowledge Infrastructure(CNKI) database and Baidu academic pool total randomized clinical test (RCT), a systematic description and analysis Meta to meet the requirements of RCT. Results Eight RCT were finally included. A total of 774 patients met the inclusion criteria. The results of Meta analysis showed that compared with the control group, the clinical efficacy of the nasal septum correction group was significantly higher than that of the control group (Z=5.47, P<0.01, OR=5.89, 95%CI:3.12~11.12); the clinical curative effect of nasal septum surgery after 6 months in the treatment group was significantly higher than the control effect (Z=3.39, P<0.01, OR=5.49, 95%CI:2.05~14.07); nasal resistance results show that the correction of nasal septum surgery group was significantly lower than the control group (Z=31.08, P<0.01, OR=-0.28, 95% CI:-0.30~-0.26). Conclusion Compared with conservative treatment, endoscopic correction of nasal septum deviation can significantly improve the clinical symptoms of perennial allergic rhinitis with nasal septum deviation. The curative effect is definite, but the long-term effect is worth further study.

Key words: endoscopic sinus surgery, deviation of nasal septum, allergic rhinitis, clinical curative effect, Meta analysis

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