Journal of Capital Medical University ›› 2019, Vol. 40 ›› Issue (2): 205-208.doi: 10.3969/j.issn.1006-7795.2019.02.010

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Current status of research concerning neuroinflammation schizophrenia

Ma Chao1, Jia Hongxiao1,2   

  1. 1. Chinese Medicine Research Center, Beijing Anding Hospital, Capital Medical University, Beijing 100088, China;
    2. Beijing Key Laboratory for Mental Disorders and Treatment, Beijing 100088, China
  • Received:2019-01-18 Online:2019-03-21 Published:2019-04-15
  • Supported by:
    This study was supported by National Natural Science Foundation of China (81873398),Capital Health Research and Development of Special Founding (2018-1-2122), Beijing Traditional Chinese Medicine Science and Technology Development Foundation(JJ2018-42).

Abstract: Schizophrenia is a common mental disorder, the mechanism of which remains unknown at present. Many hypotheses have been put forward. As early as the 1980s, three were the clinical studies showing that schizophrenia activated the inflammatory response and the immune system disorders in the peripheral nervous system and the brain. In recent years, psychiatric drugs and anti-inflammatory drugs are used in combination to improve the symptoms in schizophrenic patients, suggesting that nerve inflammation played a role in the onset of schizophrenia. The neuroinflammation effects on schizophrenia are reviewed in this article.

Key words: schizophrenia, neuroinflammation, cytokines

CLC Number: