Journal of Capital Medical University ›› 1991, Vol. 12 ›› Issue (3): 188-192.

• 论著 • Previous Articles     Next Articles

A Study of Toxicology of the Mai Tong Ling Ⅰ、Ⅱ on Evaluation of its Safety

Li Juan, Jing Zhicheng, Chen Zhenliang, Zhao Shuzhen, Zhang Hongwei, Su Yilan   

  1. Department of Industrial Health, Capital Institute of Medicine
  • Received:1991-01-09 Revised:1900-01-01 Online:1991-07-15 Published:1991-07-15

Abstract: Mai Tong Ling Ⅰ、Ⅱ are prescriptions of Chinese herbal medicine which is effective to vasculitis,made by Beijing Xuanwu Hospital of Chinese Traditional medicine.We carried out the acutetoxicity,accumulative toxicity test and mutagenic assays of Mai Tong Ling Ⅰ、Ⅱ. The results showed that the LD50 by the oral route in mice and in rate were both more than 100 ml/kg.The accumulative effect was vory low.Micronucleus test of mice bonemarrow, Ames test and analysis of spermary chromosome aberration in mice testes were all negative, mutagemicity wasn't discovered.Thus,we think that Mai Tong Ling Ⅰ、Ⅱ are relatively safe,it may be used to treat vasculitis

Key words: vasculitis, toxicology, evaluation