Recovery of Rotational Behavior After SCG Transplantaton in 6-OHDA-Induced Parkinson Model Rat

Journal of Capital Medical University ›› 1993, Vol. 14 ›› Issue (2): 120-123.

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Recovery of Rotational Behavior After SCG Transplantaton in 6-OHDA-Induced Parkinson Model Rat

Du Jianxin¹, Itakura T², Ding Yuji¹

1. Department of Neurosurgery, Xuanwu Hospital, Capital Institute of Medicine;2. Department of Neurosurgery, Wakayama Hospital, Japan

Received:1991-12-09 Revised:1900-01-01 Online:1993-04-15 Published:1993-04-15

Abstract

Abstract: Autologous superior cervical ganglion transplantation was performed into the different places in rat’s brain where the nigro-striatal dopamine system was unilaterally destoried by 6-OHDA injection.Two different locations for grafts were tested,namely the caudate and the putament.Almost the same effect on recovering ratationlal behaviour induced by apo-morphine was acheived in both groups.The intensity of ratation was about 50 per cent de-crease afer grafting.Catecholamine fluroscence histoehemical study showed good survival of grafted tissue.

Key words: transplantation, superior cervical ganglion, putament, caudate

CLC Number:

R742.5

Du Jianxin;Itakura T;Ding Yuji. Recovery of Rotational Behavior After SCG Transplantaton in 6-OHDA-Induced Parkinson Model Rat[J]. Journal of Capital Medical University, 1993, 14(2): 120-123.

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Recovery of Rotational Behavior After SCG Transplantaton in 6-OHDA-Induced Parkinson Model Rat

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