The Studies on the Links between Release of the Serum Gastrin and Helicobacter Pylori Infection in Duoderal Ulcer

Journal of Capital Medical University ›› 1993, Vol. 14 ›› Issue (2): 128-131.

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The Studies on the Links between Release of the Serum Gastrin and Helicobacter Pylori Infection in Duoderal Ulcer

Liang Peixia¹, Yang Zhaoxu¹, Chen Jingjing², Zhuang Tao², Zhang Shaodong³, Sheng Shuli³

1. Beijing Tiantan Hospital, Capital Institute of Medicine;2. Chinese Academy of Prophylactic Medical Sciences;3. Beijing Neurosurgical Institute

Received:1992-04-17 Revised:1900-01-01 Online:1993-04-15 Published:1993-04-15

Abstract

Abstract: The multiple approaches to determine HP infection were studied before and after the treatment of duodenal ulcer(DU).The approaches included the culture of HP in antral biop-sies;the Giemsa staining of histological sections;urease test and serum anti-HP IgG antibo-dies measurement with and ELISA technique;the serium gastrin(RIA) was simultaneously controled.The results show that there was significnat rise in anti-HP IgG titre and level of serum gastrin,and after the clearance of HP,the level of serum gastrin and anti-HP antibody titres significantly decreased.The results supported the hypothesis that HP infection causes DU as well as the increase of serum gastrin release.Both serology and the gastrin measure-ment may be helpful in assessmont of the effect of clinical treatment and epidenilogical stud-ies.

Key words: duodenal ulcer, helicobacter pylori, serium gastrin, Ig antibody

CLC Number:

R573.1

Liang Peixia;Yang Zhaoxu;Chen Jingjing;Zhuang Tao;Zhang Shaodong;Sheng Shuli. The Studies on the Links between Release of the Serum Gastrin and Helicobacter Pylori Infection in Duoderal Ulcer[J]. Journal of Capital Medical University, 1993, 14(2): 128-131.

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The Studies on the Links between Release of the Serum Gastrin and Helicobacter Pylori Infection in Duoderal Ulcer

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