Journal of Capital Medical University ›› 1996, Vol. 17 ›› Issue (4): 267-269.

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The Study of the Relationship between Laminin and Intracranial Astrocytoma Differentiation and Metastasis

Shi Xiaolin1, Weng Jing1, Xu Qing1, Liang Yuanjing1, Xu Qingzhong2   

  1. 1. Department of Reproductive Medicine, Capital University of Medical Sciences;2. Department of Pathology, Xuanwu Hospital, Affiliate of Capital University of Medical Sciences
  • Received:1995-12-23 Revised:1900-01-01 Online:1996-10-15 Published:1996-10-15

Abstract:

The distribution of laminin (LN) in astrocytoma of various stages of differentiation were observed to study the relationship between laminin and intracranial astrocytoma differentiation and metastasis.LSAB immunohistochemistry method was showed laminin.The laminin distributed mainly in the glial and vascular basement membrane.Astrocytoma show structure of ring upon ring around blood vessels.Glioblastoma show multilayer fibriosis structure.The LN reaction of the vascular basement membrane dicreased,showed positive.According to the malignancy of the tumor.

Key words: laminin astrocytoma, immunohistochemistry

CLC Number: