Abstract:

The morphologic changes of the endometrium were studied in 158 patients using IUD (144 patients were childbearing age, 14 were menopause age). The results showed that the morphologic features of endometrium were asynchronous with the menstrual cycle (63.4%). The foreign gaint cells were significantly increased with time (P<0.01). However neutrophilic granulocytes, plasma cells and monocytes remained unchanged. The results suggested that asynchronism of endometrium and blastocyst development may be one of the main contraceptive mechanism of IUD.

Key words: IUD, endometrium, histopathology