Abstract: The relationship between sensitized lym phocytes and early rejection of recipient was studied by detecting sensitized lymphocyte of 41 cases before and after renaltransplantation.The results showed that 14 cases out of 41 recipients suffered from acute rejections. Before operation ,the mean OD value of sensitized lym phocyte was 0.56 ±0.20 in rejections cases(14 cases) ,0.56 ±0.23 in infection cases (5 cases) ,and 0.32 ±0.05 in stable renal function cases (22 cases) ;after operation ,the values changed to 0.64 ±0.19 ,0.46 ±0.07 ,and 0.38 ±0.08 respectively.In acute rejection phase ,the above values altered dramatically before and aftertreatment of ATG. The result suggested thatit was helpfulto predict the early rejection following renal transplantation by detecting the status of recipients sensitized ly mphocytes preoperatively and postoperatively.It was also guidable for the treatment of ATG.

Key words: transplantation, sensitized lymphocyte, acute rejection