Abstract: To explore the relative importance of risk factors on microalbuminuria in the patients with disorder of glucose metabolism, a 5-year follow up of 541 patients with disorder of glucose metabolism, aged (56±11) years at baseline with UAER<20μg/min was carried out. The cases of UAER ≥20μg/min were 20.9% (113/541). Key risk factors included hypertensive duration, blood pressure, or smoking. Independent risk factors, as assessed by multiple stepwise regression effects, were SBP(P=0.000), OGTT 2h blood glucose (P=0.014). Microalbuminuria is significantly correlated with blood pressure and hyperglycemia, which suggests that early intervention is necessary.

Key words: disorder of glucose metabolism, urine albumin excretion rate(UAER), diabetic nephropathy