Journal of Capital Medical University ›› 2008, Vol. 29 ›› Issue (4): 423-427.

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Evaluation of Cognitive Functions and Its Corelation with Psychiatric Symptoms in Patients with Schizophrenia

Wang Xue1, Ren Yanping1, He Jiali1, Zhou Dongfeng2   

  1. 1. Beijing Anding Hospital, Capital Medical University;2. Sixth Hospital, Peking University
  • Received:2008-06-08 Revised:1900-01-01 Online:2008-08-24 Published:2008-08-24

Abstract: Objective To evaluate the cognitive function and its correlation with psychiatric symptoms in patients with schizophrenia.Methods Thirty-one patients with schizophrenia and thirty-one healthy person as control were evaluated by neuropsychological test,such as continuous performance test(CPT),wisconsin card sorting test(WSCT),stroop color-word test and repeatable battery for the assessment of neuropsychological status(RBANS),and the positive and negative syndrome scale(PANSS) in schizophrenic patients.Results The scores in all items of neuropsychological test except the A,B,C wrong numbers of Stroop color-word test in schizophrenic patients were significantly poorer than those in healthy controls(P<0.05).The correct time in CPT,the random wrong number in WSCT,word interference time and color interference time in Stroop color-word test,immediate memory score and total score in RBANS were significantly correlated with part of the scores in PANSS(P<0.05).Conclusion The memory,attention,executive performance and verbal function were impaired,and some cognitive function scores were significantly correlated with the psychiatric symptoms in patients with schizophrenia.

Key words: schizophrenia, cognitive function, psychiatric symptoms

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