Studies on Enhancing Anoxia Endurance and Anti-fatigue Function of Oxygenated Water

Journal of Capital Medical University ›› 2008, Vol. 29 ›› Issue (4): 467-470.

• 基础研究 • Previous Articles Next Articles

Studies on Enhancing Anoxia Endurance and Anti-fatigue Function of Oxygenated Water

Bi Xiaoyu¹, Qi Na¹, Yin Zhaoxue¹, Wu Jinhua², Gao Lifang¹, Cao Lige¹, Wu Tao¹, Hu Zijing¹, Su Yilan¹, Chen Zhenliang¹

1. Center of Food and Drug Safety Assessment, Capital Medical University;2. Beijing Huayixing Technology Development Academy

Received:2007-09-18 Revised:1900-01-01 Online:2008-08-24 Published:2008-08-24

Abstract

Abstract: Objective To investigate the effect of oxygenated water on anoxia endurance and anti-fatigue function in mice.Methods Mice were orally administered different doses of oxygenated water,survival time under anoxia,sodium nitrite poisoning or acute cerebral ischemia,loaded swimming time,serum urea nitrogen,plasma lactic acid content,and hepatic glycogen were determined.Results It was found that oxygenated water(2.4 mg/kg) could protract the anoxia survival time of mice under normal pressure(P<0.05).It could also significantly increase hepatic glycogen glycogen storage(P<0.05),decreased the rate of plasma lactic acid increase(P<0.05)and the area under curve(AUC) of plasma lactic acid(P<0.05)after exercise.Survival time under sodium nitrite poisoning or acute cerebral ischemia,loaded swimming time had the trend of prolong,the content of serum urea nitrogen also had the trend of descending.Conclusion Oxygenated water may enhance the ability of fatigue recovery and anoxia endurance function.

Key words: oxygynated water, anoxia, anti-fatigue, mouse

CLC Number:

Bi Xiaoyu;Qi Na;Yin Zhaoxue;Wu Jinhua;Gao Lifang;Cao Lige;Wu Tao;Hu Zijing;Su Yilan;Chen Zhenliang. Studies on Enhancing Anoxia Endurance and Anti-fatigue Function of Oxygenated Water[J]. Journal of Capital Medical University, 2008, 29(4): 467-470.

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Studies on Enhancing Anoxia Endurance and Anti-fatigue Function of Oxygenated Water

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