Effect of remote ischemic preconditioning in patients with ischemic stroke evaluated using single photon emission computed tomography imaging

doi:10.3969/j.issn.1006-7795.2013.01.002

Abstract

Abstract:

Objective To observe the changes of brain blood flow perfusion in patients with ischemic stroke in remote ischemic preconditioning group and control group before and after treatment using single photon emission computed tomography (SPECT) and to find out the value of remote ischemic preconditioning by SPECT. Methods Fifty patients seen in our hospital were selected, according to the different treatment options they were divided into two groups, 33 cases in remote ischemic preconditioning group and 17 cases in control group. The transcranial Doppler examination confirmed the presence of severe stenosis or occlusion in unilateral intracranial artery. Brain lesions and cerebral hemorrhagic lesions were excluded by magnetic resonance imaging. To analyse the result of patients with ischemic stroke in two groups, respectively, the patients underwent SPECT perfusion scan of cerebral blood flow before and after treatment.Results 1)The ratio of the impaired area to the opposite area in frontal,temporal,parietal,occipital lobe in patients of remote ischemic preconditioning group had no statistically significant difference before and after treatment (P>0.05). But in basal ganglia and thalamus, there was statistically significant difference (P<0.05). 2) The ratio of the impaired area to the opposite area in patients of control group with the above-mentioned parts had no significant difference before or after treatment (P>0.05).Conclusion Remote ischemic preconditioning can improve brain tolerance to ischemia. By SPECT, blood flow perfusion in basal ganglia and thalamus of patients were significantly improved after remote ischemic preconditioning. It is helpful to provide objective imaging evidence by SPECT.

Key words: cerebrovascular disorders, remote ischemic preconditioning, tomography, emission computed, single photon

CLC Number:

R743.31

HE Jie, JI Xunming, LI Sijie, LI Rujuan. Effect of remote ischemic preconditioning in patients with ischemic stroke evaluated using single photon emission computed tomography imaging[J]. Journal of Capital Medical University, 2013, 34(1): 6-10.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2013.01.002

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2013/V34/I1/6

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