The breakthrough in understanding immune response introduction of Nobel Prize in Physiology or Medicine 2011

doi:10.3969/j.issn.1006-7795.2011.05.017

Journal of Capital Medical University ›› 2011, Vol. 32 ›› Issue (5): 710-713.doi: 10.3969/j.issn.1006-7795.2011.05.017

• 诺贝尔奖 • Previous Articles Next Articles

The breakthrough in understanding immune response introduction of Nobel Prize in Physiology or Medicine 2011

ZHANG Ting, WANG Xiao-min

Department of Neurobiology, Beijing Institute for Neuroscience, Capital Medical University, Key Laboratory of Neurodegenerative Diseases of Ministry of Education of China, Beijing 100069, China

Received:2011-10-10 Revised:1900-01-01 Online:2011-10-21 Published:2011-10-21

Abstract

Abstract: The Nobel Prize in Physiology or Medicine 2011 is divided, with one half jointly to Bruce A. Beutler and Jules A. Hoffmann for their discoveries concerning the activation of innate immunity and the other half to Ralph M. Steinman for his discovery of the dendritic cell and its role in adaptive immunity. The detailed understanding of the immune system provided by the new Nobel laureates has given other researchers the ability to improve vaccines and to attempt to stimulate immune reactions to cancer and inflammation.

Key words: innate immunity, adaptive immunity, dendritic cell, Toll-like receptor(TLR), Nobel Prize in Physiology or Medicine

CLC Number:

R 329.2⁺5

ZHANG Ting;WANG Xiao-min. The breakthrough in understanding immune response introduction of Nobel Prize in Physiology or Medicine 2011[J]. Journal of Capital Medical University, 2011, 32(5): 710-713.

[1]	Tan Naichuan, Meng Yan, Zhao Heng. MicroRNA, enormous impact — Victor Ambros and Gary Ruvkun win the 2024 Nobel Prize in Physiology or Medicine [J]. Journal of Capital Medical University, 2024, 45(6): 1122-1130.
[2]	Wu Anqi, Luo Zeni, Jiang Yao, Wang Zhikai, Zhu Xinping, Sun Ximeng. Exploratory study on the ameliorative effects of Trichinella spiralis paramyosin on chronic inflammatory bowel disease [J]. Journal of Capital Medical University, 2024, 45(5): 891-899.
[3]	hou Yan, Wu Wei. Katalin Karikó and Drew Weissman won the Nobel Prize in Physiology or Medicine owing to their achievements in the development of mRNA vaccine against severe acute respiratory syndrome coronavirus 2 [J]. Journal of Capital Medical University, 2023, 44(5): 889-894.
[4]	Dong Lingyue, Wang Yutong. Tracing the evolutionary history of humans——Introduction of the Nobel Prize in Physiology or Medicine 2022 [J]. Journal of Capital Medical University, 2022, 43(5): 804-806.
[5]	Wang Peipei, Yang Fei. Voyage of discoveries of sensory decoders—Introduction of the Nobel Prize in Physiology or Medicine 2021 [J]. Journal of Capital Medical University, 2021, 42(5): 879-882.
[6]	Wu Yanhua, Wang Peigang, An Jing. Genetic engineering technology makes viruses no more mystery—Introduction of The Nobel Prize in Physiology or Medicine 2020 [J]. Journal of Capital Medical University, 2020, 41(6): 1010-1013.
[7]	Jiao Shiyu, Yu Baoqi, Qu Aijuan. Hypoxia inducible factor: a weight to balance the oxygen homeostasis—introduction of Nobel Prize in Physiology or Medicine 2019 [J]. Journal of Capital Medical University, 2019, 40(5): 805-809.
[8]	Wen Mingjie, Yu Minghang, Wang Xi. Discovery of cancer therapy by inhibition of negative immune regulation-the 2018 Nobel Prize in Physiology or Medicine [J]. Journal of Capital Medical University, 2018, 39(5): 765-769.
[9]	Chen Chen, Meng Yan. Ang Ⅱ activates dendritic cell to produce immune function [J]. Journal of Capital Medical University, 2017, 38(5): 709-714.
[10]	Li Yuzheng, Zhang Ting, Wang Xiaomin. Discoveries of molecular mechanisms controlling the circadian rhythm-the 2017 Nobel Prize in Physiology or Medicine [J]. Journal of Capital Medical University, 2017, 38(5): 765-769.
[11]	Guo Yixian, Zhang Lanfang, Sun Xuejing, Wan Suigui, Xia Changqing. Alloantigen immune tolerance and its mechanism in mice immunized with the ultraviolet radiation immature dendritic cells [J]. Journal of Capital Medical University, 2017, 38(3): 431-438.
[12]	Wang Mingxing, Wang Yan, Zhao Jingxia, Di Tingting, Ruan Zhitong, Meng Yujiao, Xie Xiangjiang, Zhang Lu, Lin Yan, Wang Ning, Li Ping. Dendritic cells on mice psoriasis-like lesions induced by imiquimod and the effects of Liangxue Jiedu decoction [J]. Journal of Capital Medical University, 2017, 38(2): 249-259.
[13]	Liu Jia, Yang Hui. Autophagy: intracellular “scavenger”——introduction of Nobel Prize in Physiology or Medicine 2016 [J]. Journal of Capital Medical University, 2016, 37(5): 699-702.
[14]	Zhao Limei, Cheng Yuli, Zhu Xinping. A novel therapy against parasites——the Chinese scientist first won the Nobel Prize in Physiology or Medicine 2015 [J]. Journal of Capital Medical University, 2015, 36(5): 829-833.
[15]	Wang Ke, Zhang Ting, Wang Xiaomin . "Inner GPS" in the brain——introduction of Nobel Prize in Physiology or Medicine 2014 [J]. Journal of Capital Medical University, 2014, 35(5): 671-675.

The breakthrough in understanding immune response introduction of Nobel Prize in Physiology or Medicine 2011

PDF

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments