Value of genotyping test for human papillomavirus(HPV) in women under 30 years of age with cervical lesions

doi:10.3969/j.issn.1006-7795.2015.04.014

Abstract

Abstract:

Objective To explore the application value of genotyping test for human papillomavirus(HPV) in women under 30 years of age with cervical lesions, so as to provide evidences for cervical lesion screening in young women. Methods Totally of 985 young women under 30 years of age were assigned to physical examination group, verrucous lesion group, cervical inflammation group, cervical intraepithelial neoplasia(CIN) group and cervical carcinoma group by pathological or cytological test. An analysis was performed using genotyping test for human papillomavirus(HPV) , including 13 high-risk HPV types(16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59 and 68), 5 low-risk HPV types(6, 11, 42, 43 and 44) and 3 common HPV genotypes in Chinese(53, 66 and CP8304). Results The total detection rate of HPV was 21.42%(211/985). The detection rate was 25.38%(250/985) for high risk HPV, 3.76%(37/985) for low risk HPV and 24.17% for multiple infections. There was statistically significant difference between cervical intraepithelial neoplasia and cervical carcinoma groups with physical examination group. Conclusion HPV-DNA test is very important for young women and of great value on detecting cervical carcinoma and precancerous lesion.

Key words: human papillomavirus, genetype, young woman, cervical carcinoma

CLC Number:

R446.1

Lyu Hong, Kang Xixiong, Zhang Guojun. Value of genotyping test for human papillomavirus(HPV) in women under 30 years of age with cervical lesions[J]. Journal of Capital Medical University, 2015, 36(4): 588-591.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2015.04.014

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2015/V36/I4/588

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