Discovery and Significance of Telomere and Telomerase——Introduction of Nobel Prize in Physiology or Medicine 2009

doi:10.3969/j.issn.1006-7795.2009.05.031

Journal of Capital Medical University ›› 2009, Vol. 30 ›› Issue (5): 718-722.doi: 10.3969/j.issn.1006-7795.2009.05.031

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Discovery and Significance of Telomere and Telomerase——Introduction of Nobel Prize in Physiology or Medicine 2009

ZHANG Ting, Wang Xiao-min

Department of Neurobiology, Beijing Institute for Neuroscience, Capital Medical University; Key Laboratory of Neurodegenerative Diseases of Ministry of Education of China

Received:2009-10-10 Revised:1900-01-01 Online:2009-10-21 Published:2009-10-21

Abstract

Abstract: This year’s Nobel Prize in Physiology or Medicine is awarded to three American scientists who have solved a major problem in biology: how the chromosomes can be copied in a complete way during cell divisions and how they are protected against degradation. Elizabeth H. Blackburn and Jack W. Szostak discovered that a unique DNA sequence in the telomeres protects the chromosomes from degradation. Carol W. Greider and Elizabeth H. Blackburn identified telomerase, the enzyme that makes telomere DNA. These discoveries made great contributions to promote the investigations on aging and tumor.

Key words: telomere, telomerase, Nobel Prize in Physiology or Medicine

ZHANG Ting;Wang Xiao-min. Discovery and Significance of Telomere and Telomerase——Introduction of Nobel Prize in Physiology or Medicine 2009[J]. Journal of Capital Medical University, 2009, 30(5): 718-722.

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Discovery and Significance of Telomere and Telomerase——Introduction of Nobel Prize in Physiology or Medicine 2009

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