Table of Content

15 January 1986, Volume 7 Issue 1

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论著

Routes of Entry into the Cerebellum for Lumbar and more Caudal Spinocerebellar Neurons in the Cat An Experimental Anatomical Study Using Retrograde Tracing with HRP

Xu Qunyuan;G. G rant

1986, 7(1):  1-15,8. 

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Nine kittens after a cordotomy on one side were lesioned respectivelyon the controlateral side to either the restiform body or the brachiumconjunctivum.Afterwards,the HRP was injected into the anterior orposterior lobe of the cerebellum respectively.After 3-4 days' survivaltime the animals were perfused and the retrogradely labeled neuronscaudal to L_{2/sub> were observed.The results were as follows:The columnof Clarke (CC,L3-L4)and the neurons in laminae Ⅳ-Ⅵ (L3-L5)sentuncrossed fibers passing through the restiform body.The dorsolateralnucleus (DL,L3-L5)sent crossed fibers projecting to the cerebellum bypassing through the brachium conjunctivum.The axons of theventrolateral nucleus (VL,L4-L5)and the spinocerebellar neurons inlateral part of lamina Ⅶ (L3-L4)had the same fiber courses as DL,but VL neurons only terminated in the anterior lobe.The fibersprojected by neurons in medial part of lamina Ⅶ (L6-Cal)were crossedand passed through the restiform body.The neurons in medial part oflamina Ⅷ (L3-L6)sent uncrossed fibers passing through the brachiumconjunctivum and projected to the anterior lobe.The ventromedialnucleus (VM,S1-Cal)sent crossed fibers by passing through therestiform body.The results in present study indicate that there existsome groups of neurons belonging to those of the dorsal spinocerebellartract (DSCT)in addition to neurons of the ventral spinocerebellartract (VSCT).}

Effect of Local Somatic Stimulation on Monoamines Content in Cerebrospinal Fluid

Shi Meitang

1986, 7(1):  15-18,8. 

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Electro-acupuncture stimulation of different intensity was bilaterallyapplied to rabbits'“Huantiao”points.The changes in concentrationof 5-hydroxytryptamine (5-HT),5-hydroxyindole acetic acid (5-HIAA),dopamine (DA)and norepinephrine (NE)were measured by means offluorometry.Concentrations of the four monoamines were found toincrease significantly in varying extent under strong stimulation;therewere an obvious rising of 5-HT and 5-HIAA but an obvious decreasein DA and NE concentration in case of weak stimulation and weak plusstrong stimulation.All these changes were statistieally very significantThe results indicate that the neural processes caused by the threedifferent means may not be completely the same and alterations inmonoamine concentrations can be evoked by these stimulations.Thissuggests that there is certain correlation between these chemicals andelectro-acupuncturing as well as noxious stimulation.Further study ofthe correlation mechanism is needed.

Study on Toxicity and Side Effect of Sodium Fulvate

Yuan Shengrong

1986, 7(1):  18-23,8. 

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Sodium Fulvate had anti-inflammatory,hemostatic and anti-cancereffects and was used clinically,The toxicity and side effect of SodiumFulvate were studied in the present paper.Through stimulation test on rabbit,hypersensitivity test onguinea-pig,acute toxicity test on mouse and subacute toxicity test onrabbit,Sodium Fulvate showed neither stimulation nor hypersensitiveeffect.and the acute toxicity of Sodium Fulvate was low,the ip LD50was 1728±110.57mg/kg.when Sodium Fulvate with low concentration (<0.8%)and lowdosage (approximately 10 times of therapeutic dose)was administeredinto the rabbit,no toxicity and side effect were observed.

Evaluation of Teaching Quality

Guo Decheng

1986, 7(1):  23-30,8. 

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This paper put forward a form,designed by means of Gallup polland in accordance with the charactersties of medical courses,to be filledin by the students with secret ballot.Then the forms were to beprocessed by computers to evaluate quantitatively the quality of teachingwork in relation to scientific,artistic as well as thoughtful specificitiesboth individually and collectively,practical examples illustrating theactual methods of processing were also afforded.This method was appliedto the teaching staff in Department of Anatomy in our college and provedto be successful.Analyses were made in this paper in a deep going way.

Hair Zinc and Sterility in Male

Lu Hekun

1986, 7(1):  30-32,8. 

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The content of trace elements in hair of 80 cases of sterilitas viriliswas determined with the ICAP-9000 emission spectrometer.It was foundthat there was no obvious difference in zinc content in hair neitherbetween the four kind of sterile male nor between the sterile male andfertile male.In this article the authors raised two questions fordiscussion:1)whether there is deficiency of zinc in the body of sterilemale,2)whether the zinc content in hair can reflect the zinc index inhuman bodies.

Real Time Recording of His-Purkinje Activity on an Every-beat Basis by Using Computer Processing—Spatial Logic Averaging Method

Wang Jiarui

1986, 7(1):  32-37,8. 

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On the principle of“Multiehannal Signal Processing based on logicaveraging”described by Flowers et al in 1981,we have developed a newhardware and software system for real time recording of His-Purkinje activity on an every-beat basis.The methodology and concrete problemsof this new technique were discussed.There was a close correlation between spatial logic averaging methodand His bundle electrogram recorded by catheter electrode in 9experimental dogs before and after medication.It was proved that thenon-invasive every-beat recording of His-purkinje activity might be usedinstead of the invasive intracardiac electrode.We obtained 41 satisfactory real time beat-by-beat recordings ofHis-Purkinje potential from the body surface of 46 normal subjects andarrhythmic patients (multiple premature beats,atrial fibrillation andvarious A-V block patients),who accepted the spatial logic averagingexamination.The value of this new technique in clinical practice was demonstrated

A Clinical Analysis of 262 Cases of AMI Complicated with Supraventricular Arrhythmias

Shi Shuying

1986, 7(1):  38-40,8. 

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From 1974-1984 among 1197 cases of AMI admitted into our hospital,262 cases were complicated with supraventricular arrhythmias with anincidence of 21.8%.The supraventricular arrhythmias in this group included APB,JPB,PSVT,Atrial Flutter and Atrial Fibrillation.The types,causative factors and prognosis were discussed and theresults revealed that supraventricular arrhythmias were significantly morefrequent in patients with congestive heart failure and not definitelyrelated to the location of AMI,the blood supply to the sino-atrial node,the occurrence of pericarditis and atrial injury.The mortality of AMI complicated with supraventricular arrhythmiaswas not different from that of the total group of AMI,but we consideredthat when supraventricular tachyarrhythmias especially atrial fibrillationand PSVT were secondary tn congestive heart failure,they could causethe cardiac performance to deteriorate further and the mortality toincrease significantly.If effective treatment with digoxin or cardioversion was promptlygiven to improve the cardiac performance,the mortality might bedecreased.

An Analysis of 221 Cases of Acute Upper Gastrointestinal Bleeding in Aged Patients

Pei Ying

1986, 7(1):  41-44,8. 

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Causes of upper gastrointestinal bleeding (UGB)diagnosed withemergency endoscopy in 221 aged patients were analysed.Peptic ulceroccupied 45.2%,acute and chronic gastric mucosal damage 21.3%,neoplasma 20.8%,esophageal varices 6.8% and etc.Being different fromthe patients of other age groups,gastic ulcer accounted for most casesof this group and high location of the lesion and large ulcer occuredmore frequently.There were no typical history and symtoms of gastricdisorders in many aged patients.Stomach cancer complicating UCB wasmore concentrated in the age group of 60-70,and its incidence decreasedin patients over 70 years,while no cancer was found in cases over 80years.The percentage of esophageal varix was significantly less thanthat in other age groups.No complication of endoscopy in the 221patients occured.Therefore emergency endoscopy in aged patients withUGB is also applicable and safe.

Primary Carcinoma of the Ureter:Pathologic Study of 22 Cases

Zhang Yueming

1986, 7(1):  44-47,8. 

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The pathologic data of 22 cases with primary carcinoma of the ureterfrom 1963 to 1982 were reviewed.The prognosis varied with the stagingand grading of the primary tumor and the complicating carcinomas inother sites of the urinary tract.In our experiences,the samehistopathologie features of the multiple urothelial carcinoma and themultifocal appearance of the abnormal epithelium around cancerous lesionsupported the multieentric theory for the genesis of the urothelialcarcinoma and emphasized the importance of follow-up after operation.

Study on the Analgesic Effect of Grapevine Injection

Wang Shijun

1986, 7(1):  47-50,8. 

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The finding of our studies showed that Grapevine Injection (GI)could inhibit the stretching response induced by acetic acid,increasethe pain threshold of electrical and thermal stimulation when it wasgiven to mice.Microdose injection of GI into the ventricles of brain ofmice resulted in significant increase of pain threshold,which testifiedthe site of analgesic effect of GI might be in the central nervous system.some other experiments confirmed that the analgesic effect of GI was notrelative to the morphine receptors,but was relative to the monoamine receptors.

The Combined Approaeh for Tympanoplasty

Lin Yongxiang

1986, 7(1):  51-52,8. 

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This paper was based on 5 cases (5 ears)of chronic purrullent otitismedia and mastoiditis.All these cases were treated by tympanoplastythrough a combined approach with some modification.3 years' follow-upshowed good results in 4 cases.Audiometrical improvement wasachieved in 4 cases with a maximum of 27 dB.One case failed as a resulfof reperforation of the new drum due to infection.The cause of thefailure was briefly reviewed.The authors concluded that strict selectionof the patients and good technique are the key to success.What is more,the use of double irrigation tubes after operation is beneficial to thehealing of operative wound.In one word,this method is worthyof application in otosurgery.