Improving effect of strengthening the spleen and invigorating the kidney on negative symptoms of schizophrenia patients

doi:10.3969/j.issn.1006-7795.2012.03.005

Journal of Capital Medical University ›› 2012, Vol. 33 ›› Issue (3): 307-310.doi: 10.3969/j.issn.1006-7795.2012.03.005

• 中西医结合临床与基础 • Previous Articles Next Articles

Improving effect of strengthening the spleen and invigorating the kidney on negative symptoms of schizophrenia patients

KANG Yu-chun¹, JIA Hong-xiao², ZHU Hong², LIU Jie², JIANG Zhen-kang², ZHANG Ji-zhi²

1. Department of Out-patient, Beijing Chaoyang Third Hospital, Beijing 100025, China;2. Department of Integrated TCM & Western Medicine, Beijing Anding Hospital, Capital Medical University, Beijing 100088, China

Received:2012-02-20 Revised:1900-01-01 Online:2012-06-21 Published:2012-06-21

Abstract

Abstract: Objective To investigate the improving effects on negative symptom of schizophrenia patients by strengthening the spleen and invigorating the kidney. Methods Sixty schizophrenia patients treated with chlorpromazine were divided into two groups, study group was treated with herbal mixture which can strengthen the spleen and invigorate the kidney, the control group was treated with placebo for 12 weeks. Positive and negative symptom scale (PANSS) was used to evaluate positive and negative symptoms. Results Total score of positive symptom scale and negative symptom scale, score of blunted effect, emotional withdrawal, poor rapport, passive and apathetic social withdrawal, stereotyped thinking in negative subscale significantly decreased after 12 weeks' treatment in study group compared with baseline (P<0.05). And this improving effect was superior to control group apart from positive symptom and blunted effect (P<0.05). However only score of positive symptom and blunted effect improved in control group (P<0.05). Conclusion The method which can strengthen the spleen and invigorate the kidney have improving effects on negative symptoms of schizophrenia.

Key words: schizophrenia, negative symptom, strengthening the spleen and invigorating the kidney

CLC Number:

R 256.29

KANG Yu-chun;JIA Hong-xiao;ZHU Hong;LIU Jie;JIANG Zhen-kang;ZHANG Ji-zhi. Improving effect of strengthening the spleen and invigorating the kidney on negative symptoms of schizophrenia patients[J]. Journal of Capital Medical University, 2012, 33(3): 307-310.

0
/ / Recommend

Add to citation manager EndNote|Reference Manager|ProCite|BibTeX|RefWorks

URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2012.03.005

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2012/V33/I3/307

[1]	Lian Siyuan, Wu Han, Han Jinxiang, Xiao Cunli, Ren Yanping, Jin Wenqing, Wang Wen, Ma Xin. Study of related factors on self-report effects of rehabilitation in schizophrenia patients [J]. Journal of Capital Medical University, 2022, 43(2): 233-238.
[2]	Li li, Liu Chaomeng, Ren Yanping, Yang Chunlin, Ma Xin. Research advances of modified electroconvulsive therapy for first-episode schizophrenia [J]. Journal of Capital Medical University, 2022, 43(2): 249-253.
[3]	Guo Chengwei, Zhou Jiaojiao, Feng Yuan, Yang Yunping. A comparative study of self esteem between schizophrenics and normal people [J]. Journal of Capital Medical University, 2022, 43(2): 294-298.
[4]	Chen Xi, Ma Denglei, Li Lin. Effects of icariin on the behavioral changes, demyelination and neuroinflammation in mice with cuprizone-induced schizophrenia [J]. Journal of Capital Medical University, 2021, 42(5): 761-767.
[5]	Ning Yanzhe, Zhu Hong, Song Nan, Zheng Sisi, Li Ziyan, Li Jiajia, Ma Rui, Jia Hongxiao. A preliminary study on efficacy for Shi-zhen-an-shen granules on cognitive impairments in prodromal schizophrenia [J]. Journal of Capital Medical University, 2021, 42(3): 404-407.
[6]	Yi Yuwei, Yan Fang, Jin Yuhong, Xiao Cunli. Analysis of influencing factors of risk behaviors of inpatients with schizophrenia [J]. Journal of Capital Medical University, 2021, 42(2): 323-327.
[7]	Sha Sha, Zhao Xixi, Han Chuanliang, Peng Xing, Zhang Pei, Dong Wen, Yin Jingjing, Wang Changming. Correlation between alpha activity and cognitive in resting electroencephalogram of schizophrenia [J]. Journal of Capital Medical University, 2021, 42(1): 117-124.
[8]	Zhang Ying, Wang Ruomei, Li Gang. Cognitive function, emotion management and its influencing factors in stable schizophrenia [J]. Journal of Capital Medical University, 2021, 42(1): 143-147.
[9]	Liu Xinyao, Ma Chao, Jia Hongxiao. Current status of research concerning animal models of cognitive impairment of schizophrenia [J]. Journal of Capital Medical University, 2020, 41(1): 50-54.
[10]	Ma Chao, He Yi, Sun Zuoli, Liu Xinyao, Feng Zhengtian, Chen Pei, Ning Yanzhe, Zhu Hong, Yin Dongqing, Jia Hongxiao. Analysis of effect of Shi-Zhen-An-Shen-Tang on intestinal microflora diversity of mice exposed to cuprizone based on 16S rRNA technique [J]. Journal of Capital Medical University, 2020, 41(1): 64-70.
[11]	He Xiaoxiao, Zhou Fuchun, Wang Chuanyue, Zhu Hui, Ji Xiao, Guan Hongzhi. Analysis of clinical characteristics of catatonia in psychiatric emergency [J]. Journal of Capital Medical University, 2019, 40(5): 688-692.
[12]	Zhuang Wenxu, Zhang Weibo, Zhu Youwei, Zhu Yi, Cai Jun. Lifestyle interventions for physical health conditions in patients with schizophrenia [J]. Journal of Capital Medical University, 2019, 40(5): 698-702.
[13]	Ma Chao, Jia Hongxiao. Current status of research concerning neuroinflammation schizophrenia [J]. Journal of Capital Medical University, 2019, 40(2): 205-208.
[14]	Wu Yan, Sun Zuoli, Ma Chao, Zhu Hong, Yin Dongqing, Jia Hongxiao. Effects of Yishenpingganfang, an empirical prescription on social interaction behavior in mice exposed to cuprizone and its possible action target [J]. Journal of Capital Medical University, 2019, 40(2): 209-213.
[15]	Yin Dongqing, Huang Fang, Zhao Anquan, Wang Qunsong, MA Yanbing, Chen Jindong, Li Baojun, Du Hong, Jia Hongxiao. Establishing traditional Chinese medicine pattern elements diagnostic scale of schizophrenia [J]. Journal of Capital Medical University, 2018, 39(6): 821-827.

Improving effect of strengthening the spleen and invigorating the kidney on negative symptoms of schizophrenia patients

PDF

Knowledge

Cited

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments