The Study of c-erb B Oncogene Amplification in Human Brain Tumour

Journal of Capital Medical University ›› 1993, Vol. 14 ›› Issue (4): 247-249.

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The Study of c-erb B Oncogene Amplification in Human Brain Tumour

Tian Jingsheng¹, Deng Feng¹, Tian Hua¹, Zheng Shaopeng², Xu Qunyuan²

1. Beijing Institute for Cancer Research;2. Xu Qunyuan Beijing Institute for Neurosciences, Capital Institute of Medicine

Received:1993-09-01 Revised:1900-01-01 Online:1993-10-15 Published:1993-10-15

Abstract

Abstract: Oneogenes appear to be involved in tumorigenesis of human brain tumours via qualita-tive and quantitative alterations.Twenty eases of the human brain turnouts were studied by DNA amplification with the dot blot method.c-erb B(0.5 kb)oncogene was used as probe. The result showed that the c-erb B amplification was found in seven menigioma and ten cases of glioma Ⅲ or glioblastoma multiform.It is suggested that c-erb B oneogene plays an important role in the development of human brain tumour.

Key words: human brain tumour, oncogene amplification, c-erb B oneogene

CLC Number:

R739.41

Tian Jingsheng;Deng Feng;Tian Hua;Zheng Shaopeng;Xu Qunyuan. The Study of c-erb B Oncogene Amplification in Human Brain Tumour[J]. Journal of Capital Medical University, 1993, 14(4): 247-249.

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The Study of c-erb B Oncogene Amplification in Human Brain Tumour

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