Abstract: To study the relationship of slight albuminuria(microalbuminuria)to serum lipids and lipoproteins in elder NIDDM, the levels of plasma TC、TG、HDL-C、apoA、apoB、Lp(a)were determined in elder NIDDM patients with microalbuminuria and normal albuminuria and control subjects. The result showed that the levels of plasma TG Lp(a)in elder NIDDM patients with microalbuminuria were significantly higher than those in elder NIDDM patients with normal albuminuria and control subjects. The levels of plasma HDL-C、 apoA in elder NIDDM patients with microalbuminuria were significantly lower than those in elder NIDDM patients with normal albuminuria and control subjects. It is conclude that elder NIDDM patients with microalbuminuria are associated with alter lipid and lipoprotein levels. The excess cardiovascular mortality and morbidity in elder NIDDM patients with microalbuminuria may. In part, be explained by these lipidand lipoprotein abnormalities.

Key words: aged, non-insulin dependent diabetes mellitus, microalbuminuria, serum lipid, lipoprotein