Abstract: In order to study the correlation between retention of water and sodium of chronic glomerulonephritis and plasma endotheliolysin(PET). PET and 24 hours uric protein excretory volume were examined in chronic glomerulonephritis patients with or without retention of water and sodium, found that PET in the group with retention of water and sodium is obviously higher than that in the control group(P<0.01), and in the group without retenion of water and sodium,it is not obviously different from that in control group(P>0.05). It was also found that not only PET in the group with retention of water and sodium, but also the uric protein excretory volume is obviously higher than that in the group without retention of water and sodium. There is no linear correlation between PET and uric protein exeretory volume(r=0.35, t =1.23). So PET may play important role during the physiopathalogic process of chronic glomerulonephritis, but had no direct relation to uric protein excretory volume.

Key words: chronic nephritis, PET, UAE