Abstract: The aim was to illustrate the relationship between HP infection and CSG and the relationship between HP infection in CSG patients and age and gender. Retrospectively and histologically the biopsy specimens were doserved in 1 670 patients who were diagnosed as CSG clinically, endoscopically and histologically by HE staining and Giemsa staining to determine the severity and activity of CSG. The biopsy specimens were observed by Giemsa staining to determine HP infection. The incidences of HP in non-active mild, moderate and severe CSG patients were 7.35%, 31.02%, 52.03% respectively, the difference between any two incidences of the three was of statistical significance(P< 0.01), the incidences of HP in active mild,moderate and severe CSG patients were 66.67%, 71.81%, 89.43% respectively, and the difference between the incidences of HP in active mild, moderate and severe CSG patients and the correspondents in non-active CSG patients were of statistical significance(P<0.01). The incidence of HP in male patients was 36.92%, and in female patients was 33.01%. No statistical difference existed between two groups(P>0.05). the incidences of HP in age-group ≤30 years, 31～60 years and ≥61years were 33.92%, 37.90%, 28.74% respectively, with statistical difference only between age-group 31～60 years and ≥61 years(P<0.01). HP infection is a important factor that makes non-active CSG turn into active CSG; HP infection induces increase in the severity of CSG; there is no difference in the incidence of HP between male and female CSG patients; In CSG patients,HP infection is found most commonly in age-group 31～60 years.

Key words: chronic superficial gastritis, helicobacter pylori