Abstract: Objective To evaluate the diagnostic value of hPET and CT in bronchogenic carcinoma and the application of hPET and CT in combination.Methods One hundred and ninety-two inpatients with suspected lung malignancy had hPET and CT examinations which were completed before surgery.All images were analyzed visually.It was considered positive for malignancy if the ¹⁸F-FDG uptake was increased relative to that in the adjacent lung tissue and the uptake of ¹⁸F-FDG was focal.Otherwise,it was considered negative if the ¹⁸F-FDG uptake was increased in a sheet form and the margin of the uptake was blurred.If the lung lesions had positive CT signs,they were considered as malignancy.Otherwise,they were considered benign.Results One hundred and forty-five patients were proven to have lung cancer by pathology,and 47 patients had benign lung diseases.The false-negative and false-positive rates of hPET was 49.0% and 12.1%.The false-negative and false-positive of rates CT was 50.9% and 9.5%.The false-negative and false-positive of hPET combination of CT is 17.8% and 7.6%.There were no significant differences between false-positive and false-negative rates of hPET and CT.The CT results of 41 patients(21.4%) were falsely contrasted with pathological results,but hPET results of 24 patients(58.5%) were identical with pathological results.The coincidence rates of single CT or hPET with pathological results were 78.65% and 78.13%,respectively.The coincidence rate of combined application of hPET and CT with pathological results was 91.15%.Conclusion There are no significant differences of false-positive and false-negative results between single hPET and CT,but combined application of hPET and CT can improve the correct diagnosis rate of lung lesions.

Key words: lung lesions, hPET, CT