Progress in Studies on Mechanism of Hepatitis C Virus Resistance to Interferon Treatment

doi:10.3969/j.issn.1006-7795.2009.06.017

Journal of Capital Medical University ›› 2009, Vol. 30 ›› Issue (6): 799-804.doi: 10.3969/j.issn.1006-7795.2009.06.017

• 慢性丙型肝炎临床研究 • Previous Articles Next Articles

Progress in Studies on Mechanism of Hepatitis C Virus Resistance to Interferon Treatment

REN Shan, CHEN Xin-yue

International Mecicine Ward, Beijing YouAn Hospital, Capital Medical University

Received:2009-08-28 Revised:1900-01-01 Online:2009-12-21 Published:2009-12-21

Abstract

Abstract: Interferon plays a critical role in the host's natural defense against viral infections and in their treatment. Interferon is one of the two drugs that constitute the only antiviral therapy for hepatitis C virus(HCV) infection; however, in a certain proportion of cases the virus is resistant to interferon. Several HCV proteins have been shown to possess properties that enable the virus to evade the interferon-mediated cellular antiviral responses.

Key words: interferon, hepatitis C virus, viral protein, interferon resistance

CLC Number:

R 512.6⁺3

REN Shan;CHEN Xin-yue. Progress in Studies on Mechanism of Hepatitis C Virus Resistance to Interferon Treatment[J]. Journal of Capital Medical University, 2009, 30(6): 799-804.

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Progress in Studies on Mechanism of Hepatitis C Virus Resistance to Interferon Treatment

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