A Early Study about Morphogenesis of Human Papillomavirus

Journal of Capital Medical University ›› 1989, Vol. 10 ›› Issue (4): 260-263.

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A Early Study about Morphogenesis of Human Papillomavirus

Zhang Lining¹, Gao Tianxiang², Sun Yeping³

1. Laboratory of Electron Microscopy, Shandong Medical University;2. Laboratory of Electron Microscopy, Capital Institute of Medicine;3. Centre Laboratory of Affiliated Hospiral, Shandong Medical University

Received:1989-03-02 Revised:1900-01-01 Online:1989-10-15 Published:1989-10-15

Abstract

Abstract: Ultrastructure of eleven common warts and two plantar warts were studied by transmitional electron microscopy. HPV antigens were localizied by immunohistochemical staining. Results showed that there was no viral particals or antigen in the stratum basale and lower or middle stratum spinosum. The viruses and antigens were mainly found in stratum granulosum and corneum, sometimes in upper stratum spinusum. "Pre-virus particlesn" were seen in upper stratum spinusum. A morphogenetic course of HPV in squamous epithelial cells was discovered.

Key words: human papillomavirus, immunohistochemical staining, morphgenesis

Zhang Lining;Gao Tianxiang;Sun Yeping. A Early Study about Morphogenesis of Human Papillomavirus[J]. Journal of Capital Medical University, 1989, 10(4): 260-263.

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A Early Study about Morphogenesis of Human Papillomavirus

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