Journal of Capital Medical University ›› 1996, Vol. 17 ›› Issue (3): 197-200.

• 论著 • Previous Articles     Next Articles

Distribution and Numerical Changes of PCNA Labelling Cells during Estrus Cycle and Pregnancy of Mouse

Shi Xiaolin1, Li Guixian1, Ma Xiaorui1, Xu Qin1, Sasaki H2, Tominaga T2   

  1. 1. Center of Reproductive Medicine, Capital University of Medical Sciences;2. Department of Obstetrics and Gymeclogy, Fukui Medical School, Japan
  • Received:1900-01-01 Revised:1995-09-26 Online:1996-07-15 Published:1996-07-15

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Abstract: Sixty BDF1 female mice were divided into two groups: estrus cycle and pregnancy (day 4～10).The endometrium of mice were studied by immunohistochemistry.The proliferating cell nuclear antigen (PCNA) labelling index (%) was studied throughout estrus cycle and pregnancy.The results suggested that:①In estrus the number of PCNA labelling cells was the highest.These cells were 21.8% of all kinds of endometrium cells.They distributed mainly over superficial epithelium (60% of superficial epithelium).There was a slight increase of the PCNA cell in the disestrus (9.4% of all kinds of endoinetrium cells).They also distributed mainly over superficial epithelium (26% of superficial epithelium).②In pregnancy the PCNA labelling cell distributed mainly over upper decidua.They were the highest (14% ) in decidua of 9 th day of pregnancy.

Key words: PCNA cell, endometrium, immunohistochemistry

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