Abstract: The aim was to explore the possible risk factor for death patients with Severe Acute Respiratory Syndrome.15 death SARS patients from March to June 2003 were analyzed.Results: Age: 23 to 81years old, average age were (50.7±18.8) years old, 7 patients were more than 50 years old.Underlying disease: 5 patients with diabetes, 5 patients with hypertension, 2 patients with chronic renal function failure and uraemia.T subset: CD⁴⁺ T lymphocyte decreased significantly at the first week of disease period and average CD⁴⁺T count were (248±82)cells/μL, average CD⁴⁺ T count were (181±128)cells/μL at second week and (125±46)cells/μL at third week, compared with group of cured patients, it had significantly difference(P<0.05).Chest image: chest image of 7 patients was apparent of pan-ground glass and consolidation in bilateral lung lobes.CK and CK-MB: average CK were ( 269.3± 399.9)U/L and CK-MB were (31.1±26.1)U/L.The adverse clinical outcome will be shown if SARS patient with older age, multi-underlying disease, rapid decrease in T subset, rapid progress of appearance of pan-consolidation in chest image, elevate of CK and CK-MB.

Key words: severe acute respiratory syndrome(SARS), death, risk factor