Abstract:

Objective To study the effect of excessive dose of Ginkgo biloba L leaves capsule on antioxidants level in serum of dogs.Methods Six dogs were fed excessive dose of Ginkgo biloba L leaves capsule. SOD and GSH-Px in serum of dogs' were measured by methods of ultraviolet visible spetrophotometry; LPO were measured by means of fluorescence spectroscopy methods.Results The activity of SOD after capsules taken were lower than that before capsule feeding. Seven to 10 h after capsules taken SOD's level was decreased significantly( P <0.01). GSH-Px's level was decreased 10 h after feeding( P <0.01). LPO was decreased in 5 h and increased in 7～12 h after capsules taken( P <0.01).Conclusion The animals are in state of oxidetine stree and ability of antioxidant of dogs is decreased after excessive ginkgo biloba L leaves capsule was taken.

Key words: ginkgo biloba L, dog, antioxidant, serum