Abstract: Objective To investigate lipidemia disorder and effect of glucose on lipidemia in patients with type 2 diabetes(T2DM).Methods 200 patients with T2DM were enrolled and the levels of blood lipid(TG,TC,HDL,LDL),serum insulin(Ins),plasma glucose(PG),HbA1c were measured.Results 1)HbA1c was correlated with TG,TC,LDL positively(P<0.05),and correlated with HDL negatively(P<0.05).2)The levels of fasting TG,TC,LDL were significantly increased and HDL remarkably decreased following increasing of HbA1c.Conclusion Patients with T2DM have marked disorder of blood lipid.The levels of glucose and lipid should be both controlled to prevent atherosclerosis.

Key words: diabetes mellitus, HbA1c, dyslipoproteinemia