Study on the Activity of CD69 and L-2 before and after Operationin Colon Cancer Patients

Journal of Capital Medical University ›› 2007, Vol. 28 ›› Issue (1): 20-22.

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Study on the Activity of CD69 and L-2 before and after Operationin Colon Cancer Patients

Jia Jianguo¹, Sun Jiabang¹, Liu Dachuan¹, Feng Xiuli², Chen Hong¹, Yang Lei¹, Yang Peng¹, Li Fei¹

1. Department of General Surgery, Xuanwu Hospital, Capital Medical University;2. National Human Genomic Research Center

Received:2006-12-18 Revised:1900-01-01 Online:2007-02-24 Published:2007-02-24

Abstract

Abstract:

Objective To test the change of immunity function after colon cancer operation. Methods Test the activity of CD69 and level of L-2 by cell flow cytometer after colon cancer operation in 33 cases. Results The activity of CD69 was significantly higher after operation 1st day compared with nonoperation patients, and the activity of CD69 expression is unchange from the after operation 3 d to 10 d. The level of L-2 was nondifferent from the first day to third day after operation. The level of L-2 was higher 5 d after operation than the control group(P<0.05 ), the level of L-2 10 d after operation was significantly higher than unoperation group(P<0.01). Conclusion The immunity function is inhibited in colon cancer patients. The ability of anticancer and immunity function is improved after colon cancer operation.

Key words: colon cancer, immunity, CD69, L-2, cell flow cytometer

CLC Number:

R656.9

Jia Jianguo;Sun Jiabang;Liu Dachuan;Feng Xiuli;Chen Hong;Yang Lei;Yang Peng;Li Fei. Study on the Activity of CD69 and L-2 before and after Operationin Colon Cancer Patients[J]. Journal of Capital Medical University, 2007, 28(1): 20-22.

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Study on the Activity of CD69 and L-2 before and after Operationin Colon Cancer Patients

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