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    Effect of tongfu granules on intestinal microflora barrier function in rats with antibiotic-associated colitis
    LI Dan;REN Ai-min;WANG Hong;XU Shu-zhen
    Journal of Capital Medical University    2012, 33 (3): 315-321.   DOI: 10.3969/j.issn.1006-7795.2012.03.007
    Abstract1134)      PDF(pc) (2698KB)(6294)       Save
    Objective To investigate the effects of Tongfu granules on intestinal microflora barrier function in rats with antibiotic-associated colitis. Tongfu granules which is a kind of Chinese traditional medicine. The present study aimed to investigate protecting effect of the medicine on impaired intestinal mucosa, and further study effects of Dahuang and Houpo which are the two main components of Tongfu granules. Methods Eighty male rats were divided into ten groups. After making the models of Lincomycin induced antibiotic-associated colitis, blood samples of rats were taken for measuring endotoxin.The colonic contents of rats were collected to culture four floras: bacillus acidi lactici, bacillus bifidus, enterococci bacillus coli. The pathological change of intestinal mucosa was observed using light microscope. Results The body weight of the model group was significantly decreased, a significant difference was shown between Houpo and Tongfu granule in weight. The endotoxin in rats of treatment group was decreased. But insignificant difference was shown among Dahuang, Houpo and Tongfu granule groups in endotoxin. There was a significant difference (P<0.05) between Tongfu granule and model group after treatment. The number of bacillus acidi lactici, bacillus bifidus, enterococci bacillus coli increased. The scores of the lesions showed a significant difference between Tongfu granule and Dahuang. Conclusion There was injury in intestinal mucosal barrier in antibiotic-associated colitis rats. Chinese Traditional medicine Tongfu granules Dahuang and Houpo had protective effects on the smalI intestinal barrier. They can decrease the endotoxin level of antibiotic-associated colitis rats. They also could recover the intestinal flora. Tongfu granule was better than Dahuang and Houpo.
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    Cited: Baidu(3)
    Analysis of imaging characteristics, treatment and prognostic factors of primary abdominal cocoon
    LI You-guo;SONG Mao-min;BAI Ri-xing;ZHENG Jian-wei;YUAN Hui-sheng
    Journal of Capital Medical University    2012, 33 (1): 74-78.   DOI: 10.3969/j.issn.1006-7795.2012.01.015
    Abstract1095)      PDF(pc) (1155KB)(4824)       Save
    Objective To investigate the imaging characteristics and prognostic factors of primary abdominal cocoon.Methods The clinical features, CT information, treatment and prognosis of patients with primary abdominal cocoon in Beijing Tiantan Hospital from January 2000 to December 2009 were retrospectively analyzed.Results All 6 patients showed an obstruction. Abdominal plain X-ray showed intestinal loop expansion of product gas and liquid gas plane in the small bowel. Abdominal CT examination showed a conglomeration of multiple small bowel loops encapsulated in a thickened capsule. Abdominal ultrasound examination showed some expansion of small bowel and 4 patients showed a small amount of ascites. Five patients had barium meal examination, all demonstrated barium slowly moved through the distal ileum, with one of the 5 patients showing stenosis in the distal ileum, another one showed complete obstruction. Laparotomy revealed that all or part of the small intestine was wrapped by a layer of dense gray tough fibrous membrane and the omentum was absent. All the patients underwent partial fiber membrane cystectomy, adhesion lysis, etc., 1 case underwent partial small bowel resection. All patients were cured.Conclusion Gastrointestinal imaging and abdominal CT examination has important diagnostic value for primary abdominal cocoon. Surgery is a safe and effective treatment.
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    Cited: Baidu(2)
    Studies on Dynamic Changes of Antibody Production in Rat Regionalymph Nodes by Using Horseradish Peroxidase as Tracing Substance
    Li Hui;Gao Tianxiang;长谷川
    Journal of Capital Medical University    1991, 12 (1): 10-15.  
    Abstract602)      PDF(pc) (3004KB)(677)       Save
    After being mixed with Frund's adjuvant,horseradish peroxidase was used as antigen and injected into rat paw.Dynamic studies was carried out on:1.the retention time of antigen in local lymph nodes;2.the processing of antigen by macrophages;3.the effect on the synthesis of other unrelated immunoglubins after antigen stimulation.Four different histochemical and immunohistochemical methods were compared with light microscopy.Our results proved that the application of HRP,DAB and H2O2 as tracer substance and substrate for the studies on topics of cell biology and pathology makes it possible to observe the reaction products both in light microscope and electron microscope.It also permites to carry out comparative studies both at the bellular and ultrastractural levels.
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    Progress on the injury and repair mechanism of renal tubular epithelial cells in the transition of acute kidney injury to chronic kidney disease
    Chen Xiaomei, Ma Yuanyuan, Nie Jing, Zhu Fengxin
    Journal of Capital Medical University    2022, 43 (5): 720-727.   DOI: 10.3969/j.issn.1006-7795.2022.05.009
    Abstract602)      PDF(pc) (1051KB)(1982)       Save
    Acute kidney injury (AKI) is a clinical syndrome caused by various factors and characterized by renal function declines sharply in a short period of time. AKI, an independent risk factor of chronic kidney disease (CKD) and end-stage renal disease, is associated with high levels of morbidity and mortality. Currently, the treatments for AKI and the prevention of the transition of AKI to CKD are very limited. Therefore, it is essential to explore the mechanism of AKI to CKD. Renal tubular epithelial cells (RTECs) are the major cells of the kidney and are vulnerable to various biological stresses, such as ischemia, hypoxia and toxins.RTECs are also key inflammatory and fibrogenic cells that drive the progression from acute to chronic kidney disease. In view of the central role of RTECs, this review will focus on the maladaptive repair mechanisms of RTECs in the transition of AKI to CKD, providing novel targets and new strategies for effective treatment.
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    Hepatotoxicity Caused by Commonly-used Chinese Medicinal Herbs and Compound Preparation
    Wang Xiujuan;Xu Liping;Wang Min
    Journal of Capital Medical University    2007, 28 (2): 220-224.  
    Abstract1121)      PDF(pc) (466KB)(3325)       Save

    The manifestations of hepatotoxicity caused by Chinese medicinal herbs are similar with ordinary liver disease. Many pathological alterations of hepatotoxicity can be seen, such as hepatocellular damage, liver disfunction, increased serum transaminase, hepatomegalia, jaundice, cholestasis, chronic hepatitis complicated with fibrosis, hepatic cirrhosis、fulminating hepatic failure, liver tumor, and etc. In most cases, the liver damage is reversible after discontinuation. The commonly-seen herbs which may cause hepatotoxicity are Huang Yao Zi(Tuber Dioscoreae Bulbiferae)、Cang Er Zi(Fructus Xanthii Sibirici)、Lei Gong Teng(Radix Tripterygum)、Ku Lian Zi(Fructus Meliae Azedarach), etc., and the compound preparations are Zhuang Gu Guan JIe Wan(The Pill for Asthritis), Ke Yin Wan(The Pill for Psoriasis), Xiao Chai Hu Tang (Xiao Bupleuri Decoction), and so on. In addition, the improper combination of Western medication and Chinese medicinal herbs may also bring about hepatotoxicity. Except the toxicity of herbs themselves, the other factors include the dosage, time, the body constitution of patients, sensitivity, seasons, and geographic regions, etc. Therefore, the medicinal herbs and their preparations should be used rationally under the guidance of the theory of traditional Chinese medicine and differentiation of symptoms, and the medical skill should be improved, which are the effective measures for avoiding hepatotoxicity.

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    Brief report on stroke prevention and treatment in China,2024
    Stroke Prevention Project, National Health Commission, Ji Xunming
    Journal of Capital Medical University    2025, 46 (6): 947-960.   DOI: 10.3969/j.issn.1006-7795.2025.06.001
    Abstract2990)      PDF(pc) (5215KB)(1649)       Save
    lthough China has a slight decline in stroke incidence in recent years, it still seems to be the leading health threat to Chinese citizens. China continues to bear a heavy stroke burden which has distinct epidemiological characteristics, while major risk factors remain prevalent and poorly controlled. Markedly, the government is putting effort into advancing the stroke prevention and treatment system, meanwhile, continuously funding cerebrovascular disease research, and driving steady improvements in diagnosis and treatment capabilities. However,  stroke prevention and control work in China still faces considerable challenges. This report systematically reviews the current state of stroke prevention and treatment in China during 2023 from five perspectives: epidemiological characteristics, risk factors, diagnostic and therapeutic advances, prevention system development and stroke center construction, aiming to provide references for clinical practice.
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    Characteristics and governance of retracted papers from “paper mills”
    Zhang Jianjun, Zhuang Ying, Sun Chaoyuan, Gao Jian, Yan Hong, Jin Haizheng
    Journal of Capital Medical University    2026, 47 (1): 202-211.   DOI: 10.3969/j.issn.1006-7795.2026.01.026
    Abstract129)      PDF(pc) (639KB)(1571)       Save
    Objective  To systematically analyze the characteristics of articles retracted due to “paper mills” and explore effective governance strategies to uphold academic integrity. Methods  Based on data from the Retraction Watch Database (2010-2024), a total of 7 513 articles retracted due to “paper mills” were included. Descriptive statistics and categorical analysis were employed to examine disciplinary distribution, national characteristics, article types, retraction timelines, publisher sources, and retraction reasons. Results  Retracted articles were primarily concentrated in Business & Technology (48.3%) and Basic Life Sciences (38.1%). China (including Taiwan Province) contributed to 88.5% of global retractions. Research articles constituted the majority of retracted types (88.3%). The average retraction period was 761.5 d. Publishers such as Hindawi and IOP Publishing were major sources of retractions. Key contributing factors included third-party investigations, data irregularities, and peer review fraud. Conclusion  Retractions linked to “paper mills” exhibit features such as disciplinary concentration, geographical imbalance, publisher accountability deficits, and retraction delays. Multifaceted governance strategies—including reforming academic evaluation systems, strengthening journal review mechanisms, promoting international cooperation, and enhancing research ethics education—are essential to combat paper mill activities and safeguard the integrity of scientific research.
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    Analysis of clinical characteristics of robot-assisted surgery in traumatic orthopedics
    Li Minjuan, Zhang Teng, Jia Zhao, Han Wei , Wang Junqiang, Gong Maoqi, Jiang Xieyuan
    Journal of Capital Medical University    2025, 46 (6): 1102-1109.   DOI: 10.3969/j.issn.1006-7795.2025.06.018
    Abstract129)      PDF(pc) (5442KB)(1558)       Save
    Objective  To describe the clinical application characteristics of robot-assisted technology in traumatic orthopedics based on real world data. Methods  Based on the orthopedic surgical robot database, this paper retrospectively included the basic information, epidemiological data, clinical diagnosis and surgical treatment data of inpatients undergoing surgery in the orthopedic Department of orthopedic trauma in Beijing Jishuitan Hospital Affiliated to Capital Medical University from January 2021 to July 2023. Gender, age, surgical site, surgical type, surgical time and blood loss were compared between robot-assisted surgery and non-robot-assisted surgery groups. Results There were significant differences in gender, age between the robot-assisted surgery group and the non-robot-assisted surgery group (P<0.001). Robot-assisted surgery technology has been used in 14 sites of fracture surgery. The majority of participants receiving robot-assisted surgery were male (60.61%), and patients aged 50 years and above accounted for 39.96%, among which 88.07% of patients received closed reduction internal fixation [the top three surgical sites: femur (35.48%), pelvis (26.67%) and clavicle (20.86%)]. Conclusions  Robot- assisted surgery has been widely used in traumatic orthopaedic multi-site fracture surgery, but the specific application of this technology is still different among different sites.
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    The application of artificial intelligence in stomatology
    Xie Lizhe , Yan Bin , Wang Lin
    Journal of Capital Medical University    2025, 46 (6): 968-976.   DOI: 10.3969/j.issn.1006-7795.2025.06.003
    Abstract220)      PDF(pc) (3267KB)(1526)       Save
    With the rapid development of artificial intelligence (AI) technology, it has been deeply integrated into the entire workflow of stomatological diagnosis and treatment, and it is widely applied in key aspects such as prevention, diagnosis, treatment, risk assessment, and prognosis evaluation. Herein we systematically reviews the research progress and application status of AI technology in stomatological diagnosis and treatment, focuses on the implementation effects of core technologies in typical clinical scenarios of stomatology, conducts an in-depth analysis of the major bottlenecks and challenges encountered in current practice, and puts forward a forward-looking prospect for its future development. It aims to provide a theoretical basis and practical reference for the construction and optimization of the intelligent diagnosis and treatment system in stomatology.
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    Influencing factors of female sexual dysfunction in Chinese women
    Ju Rui, Ruan Xiangyan, Dai Yinmei, Bai Yongtao, Yang Yu, Xu Xin, Cheng Jiaojiao, Yang Xingzi, Shi Yanhong, Sun Yanhua, Li Ruiling
    Journal of Capital Medical University    2022, 43 (3): 357-363.   DOI: 10.3969/j.issn.1006-7795.2022.03.005
    Abstract699)      PDF(pc) (1108KB)(1602)       Save
    Objective To investigate the risk factors of female sexual dysfunction (FSD) in Chinese women and to provide clinical evidences for improving perimenopausal and postmenopausal women's quality of life. Methods A multicenter clinical study was conducted among 902 women in the Department of Gynecological Endocrinology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University and other two medical alliance institutions from April 2020 to March 2021. Socio-demographic, behavioral and clinical data were collected. The anthropometric indices of each subject were measured. FSD were evaluated using the Female Sexual Function Index (FSFI) and the subjects were divided into two groups according to the FSFI: FSD group and no FSD group. According to the 2011 stages of the Reproductive Ageing Workshop (STRAW+10) and postmenopausal women using menopause hormone therapy (MHT) or not, the subjects were divided into seven stages, Modified Kupperman Index (KMI) for climacteric syndromes, The Patient Health Questionnaire-9 (PHQ-9) for depression, the International Consultation on Incontinent Questionnaire (ICIQ) for stress urinary incontinence, the Overactive Bladder Symptom Score (OABSS) for overactive bladder. According to the obtained results, univariate and multivariate Logistic regression analyses were performed. Results Multivariate regression analysis revealed that KMI (OR=1.061,95%CI:1.039-1.083),follicle stimulating hormone (FSH) (OR=1.008,95%CI:1.002-1.014),below secondary education level (OR=1.446,95%CI:1.019-2.052), depress (OR=1.814,95%CI:1.156-2.845), early postmenopausal stage (OR=1.717,95%CI:1.106-2.667), late postmenopausal stage (OR=1.905,95%CI:1.008-3.602), neutral marital relationship (OR=2.422,95%CI:1.711-3.429) and dissatisfaction marital relationship (OR=1.945,95%CI:1.018-3.717) were the important risk factors for FSD (P<0.05). Femoston was the protective factor for FSD in early menopausal women(OR=0.229,95%CI:0.059-0.889) (P<0.05). Conclusion Many psychological, physiological and social factors induce FSD. Ovarian function failure is an important risk factor for FSD. MHT was shown to have a beneficial effect on FSD.
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    Construction of a academic misconduct prevention system through “cognition-institution-technology” synergy-based  under the perspective of artificial intelligence
    Pang Xingmei, Xie Zhiyun
    Journal of Capital Medical University    2025, 46 (4): 754-761.   DOI: 10.3969/j.issn.1006-7795.2025.04.026
    Abstract141)      PDF(pc) (1324KB)(1429)       Save
    In recent years, academic misconduct has shown an alarming escalation trend.Particularly in the artificial intelligence environment, these improper behaviors have become more covert and complex,increasingly difficult to distinguish and identify. This study establishes a three-dimensional academic misconduct prevention system through enhancing stakeholder awareness, standardizing research integrity policies, and implementing advanced “dynamic adversarial” artificial intelligence generated content (AIGC) detection technologies (e.g., tracing with blockchain and neural network fingerprinting, deep learning algorithms, multimodal and cross-lingual detection).By integrating cognition, institution, and technology dimensions, the framework constructs a “value-driven-institutional-safeguarded-technology-empowered” synergistic governance model. Within dynamic environments, these three elements interact through synergistic effects and positive feedback loops to form governance synergy, providing innovative solutions for academic integrity construction.
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    Application of artificial intelligence in the study of cancer diagnosis and treatment research
    Liu Honglei, Yang Yingliang, Li Ronghao, Zhu Congmin, Zhang Xu
    Journal of Capital Medical University    2025, 46 (3): 395-400.   DOI: 10.3969/j.issn.1006-7795.2025.03.001
    Abstract325)      PDF(pc) (460KB)(1247)       Save
    As a major global public health concern, cancer has witnessed a continues  rise in both incidence and mortality rates. It pose not only a severe threat to human health but also a heavy burden on socioeconomic systems. Despite remarkable advancements in oncology research, critical challenges such as tumor heterogeneity, drug resistance, and limitations in early screening and diagnostic technologies remain to be addressed. Against this backdrop, artificial intelligence (AI), with its unique advantages in big data analysis, pattern recognition, and predictive modeling, has opened new avenues for cancer research. By integrating multi-modal data, including omics, imaging, and clinical information, AI not only accelerates investigations into fundamental tumor mechanisms but also demonstrates immense potential in areas such as early screening, biomarker discovery, and personalized treatment. These advancements have fostered a deeper integration of precision medicine and oncology. This review provides a comprehensive overview of the most recent progresses in the application of AI in cancer diagnosis and treatment research, with a focus on its practical value across diverse data types and clinical scenarios, as well as future directions for its development.
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    Research progress of exosomes miRNA in acute myocardial infarction
    Bao Boyi, Li Weiping
    Journal of Capital Medical University    2022, 43 (2): 199-204.   DOI: 10.3969/j.issn.1006-7795.2022.02.006
    Abstract429)      PDF(pc) (1003KB)(1428)       Save
    Exosomes is extracellular vesicles that are released into the extracellular space by the way of exoplasmosis. Exosomes can be used as a carrier to carry miRNA, protein,etc and transmit biological information in long distance. miRNA are endogenous and evolutionarily highly conserved non-coding RNA that combine with target mRNA to form translational repressions to achieve regulation of post transcriptional gene expression, thereby participating in pathophysiological processes such as cell growth and differentiation. Recent studies have shown that exosomes plays a role in the process of acute myocardial infarction by carrying microRNA, and have large prospect in the diagnosis and treatment of acute myocardial infarction. Therefore, this article briefly summarizes the recent research progress of exosomes miRNA in acute myocardial infarction.
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    Application research hotspot of traditional Chinese medicine informatics
    Gao Man, Li Haiyan
    Journal of Capital Medical University    2022, 43 (4): 592-599.   DOI: 10.3969/j.issn.1006-7795.2022.04.013
    Abstract483)      PDF(pc) (1014KB)(2267)       Save
    This paper summarized the popular applications of traditional Chinese medicine(TCM) informatics research to provide useful references for researchers, which include TCM clinical data mining and utilization, TCM intelligent diagnosis and treatment equipment research, Chinese medicine information research, discipline knowledge service based on TCM ancient and modern literature information, and TCM evaluation research based on big data.
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    Research progress of effects and mechanisms of paeony and total glucosides of paeony in treatment of immune-associated dermatoses
    Yang Yang, Chen Ruixuan, Min Li, Ma Zhijie, Mei Xueling,
    Journal of Capital Medical University    2024, 45 (1): 1-7.   DOI: 10. 3969/ j. issn. 1006-7795. 2024. 01. 001
    Abstract688)      PDF(pc) (1315KB)(1346)       Save
    Pharmacological studies have shown that white paeony has anti-inflammatory,immunomodulatory,hepatoprotective,and analgesic effects. In clinical practice, paeony and total glucosides of paeony are often used to treat autoimmune diseases. As the anti-inflammatory, immune-modulating and anti-oxidizing mechanisms of paeony and total glucosides of paeony are gradually understood,their clinical applications in immune-related and inflammatory skin diseases have been continuously expanded. The mechanisms such as anti-oxidation play an important role in enhancing efficacy,attenuating toxicity,and reducing disease recurrence rates. This article reviews the research progresses on the effects and mechanisms of paeony and total glucosides of paeony in the treatment of immune-related and inflammatory skin diseases, to provide a basis for in-depth research.
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    Clinical analysis and experience summary of large vulvar ulcers in women
    Gao Guangcheng, Sun Xin, Xu Ying, Zhuo Fenglin
    Journal of Capital Medical University    2021, 42 (6): 1046-1052.   DOI: 10.3969/j.issn.1006-7795.2021.06.023
    Abstract431)      PDF(pc) (16645KB)(1089)       Save
    Objective To explore the clinical manifestations and differential diagnosis of large vulvar ulcers. Methods By analyzing the clinical data of 3 patients with large vulvar ulcer and literature reports, the types and clinical manifestations of large vulvar ulcers were listed for diagnosis and differential diagnosis. Results Three cases of large vulvar ulcer were diagnosed as Behcet’s disease, fixed drug rash and acute vulvar ulcer, respectively, based on clinical manifestations and laboratory examinations. They were cured after treatments. Conclusion Acute vulvar ulcer, Behcet’s syndrome, fixed drug rash, extramammary Paget’s disease, chemical burn and radiation ulcer should be considered in the cases of large vulvar ulcers. Especially the diagnosis and differential diagnosis of Behcet’s disease and acute vulvar ulcer are more critical. Behcet’s disease can be diagnosed when patients have oral ulcer and vulvar ulcer.
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    Current status of clinical application of intelligent orthopedics
    Wang Junqiang, Jiang Xieyuan
    Journal of Capital Medical University    2024, 45 (5): 741-743.   DOI: 10.3969/j.issn.1006-7795.2024.05.001
    Abstract382)      PDF(pc) (339KB)(908)       Save
    Intelligent orthopaedics is a novel direction for the development of modern orthopaedics. It is also a key area for the clinical transformation of the world's current cutting-edge medical science and technology. At this stage, the clinical application research of intelligent orthopaedics focuses on intelligent medical engineering and intelligent medical treatment. Orthopaedic surgeons should properly understand the concept of intelligent orthopaedics, and identify that data-driven and medical-industrial crossover is the development path of intelligent orthopaedics. They should accurately grasp the connotation of intelligent orthopaedics and persist in the  the technological innovation of intelligent orthopaedics driven by clinical need. Orthopaedic surgeons should closely collaborate integrate with engineers and technicians, insist on exploring in the cross-cutting field, rationally rather than blindly applying cutting-edge engineering technologies, and strive to continuously develop innovative technologies and solutions for intelligent orthopaedics, which will greatly advance the  accurate orthopaedic treatment.
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    ood practices in Mendelian randomization: common designs, key challenges, and optimization in Mendelian randomization analysis
    Wang Jing, Zhang Guoyan, Cheng Shan
    Journal of Capital Medical University    2023, 44 (6): 1087-1094.   DOI: 10.3969/j.issn.1006-7795.2023.06.027
    Abstract1253)      PDF(pc) (529KB)(1081)       Save
    Mendelian randomization (MR) is a causal inference method that utilizes genetic variations as instrumental variables to investigate the causal relationships between exposures (various factors) and outcomes (diseases or phenotypes). This article discusses the fundamental assumptions of MR methods in biomedical research, common designs, key challenges, optimizations and the future prospects of MR. The article introduces the core assumptions of MR methods and how to select common MR design types in biomedical research. Furthermore, the article discusses the key challenges currently faced by MR studies and their solutions, such as how to select instrumental variables that meet the core assumptions, how to choose causal estimation methods in MR, and how to interpret MR results biologically. In addition, the article suggests some directions for future research. As a powerful tool, MR contributes to exploring causal relationships, selecting therapeutic intervention targets, and conducting long-term population-based intervention studies. While MR cannot fully replace randomized controlled trials, it has a wide  application in biomedical research and clinical practice, helping us to deeply understand the complex relationships between health and disease.
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    Writing norms for ethics in medical papers involving humans or laboratory animals
    Zhang Jianjun
    Journal of Capital Medical University    2025, 46 (1): 154-160.   DOI: 10.3969/j.issn.1006-7795.2025.01.024
    Abstract301)      PDF(pc) (462KB)(823)       Save
    Research ethics is an integral part of scientific research, encompassing the relationship between researchers and research subjects, as well as ethical issues that may arise during the research process. In research involving humans or laboratory animals, ethical issues become more complex and sensitive, necessitating stricter ethical norms and regulations. This article involves the examination 141 university journals in the field of medicine and health through the “China Academic Journal Database” in “Wanfang Data”, and the download of a total of 170 scientific papers involving humans or laboratory animals. Through the analysis and summarization of the ethical writing norms in these 170 papers, as well as suggestions for standardized writing, it is hopeful all to provide some references for medical researchers when writing papers. At the same time, it can also serve as a reference for medical journals in formulating ethical writing norms for medical papers involving humans or laboratory animals.
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    Research progress in the mechanism and prediction of suicide attempt in patients with depression
    Ren Yanping, Wu Han, Wang Wen, Jin Wenqing, Li Rena
    Journal of Capital Medical University    2024, 45 (1): 88-96.   DOI: 10. 3969/ j. issn. 1006-7795. 2024. 01. 015
    Abstract566)      PDF(pc) (556KB)(882)       Save
    Suicide is the act of individuals intentionally or voluntarily taking various means to end their lives. The global annual suicide mortality rate is approximately 16/100 000,which means approximately 703 000 people die from suicide every year,making it the leading cause of death. Suicide often occurs in patients among which mental illness, among which the most common is depression. Studying the mechanism of suicidal behavior in depression can provide important data support for developing measares to prevent  from suicidal ideation and suicidal behavior. The relevant factors for suicidal behavior include social,psychological,and biological factors. The article reviewed the advances related to suicidal behavior in magnetic resonance imaging,neurocognitive research,machine learning,ecological momentary assessment and digital phenotype,in order to provide reference for the development of early identification indicators for suicide risk.
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