Clinical characteristics of chronic rhinosinusitis with nasal polyps with different body mass index

doi:10.3969/j.issn.1006-7795.2022.06.013

Abstract

Abstract: Objective To analysis the clinical characteristics in chronic rhinosinusitis with nasal polyps (CRSwNP) patients with different level of body mass index (BMI). Methods A total of 448 CRSwNP patients and 308 controls with septal deviation in Beijing Tongren Hospital from 2013 to 2019 were recruited retrospectively. According to BMI levels, CRSwNP patients were divided into 2 groups: underweight & normal weight (BMI<25 kg/m²) or overweight & obese (BMI≥25 kg/m²), and the rate of asthma comorbidity and revision surgery were analyzed. Results The percentage of eosinophilis in peripheral blood and the allergy comorbidity rate in CRSwNP patients were significantly higher than those in control group (P<0.05). Further classified the patients by genders, the female patients had higher rate of asthma comorbidity (31.6% vs 20.7%), and male overweight & obese CRSwNP patients were more than female overweight & obese patients. Classified the patients by BMI levels and gender, revision surgery rate of female overweight & obese CRSwNP patients was 43.6%, which was significantly higher than that of female underweight and normal weight patients. The percentage of eosinophil in peripheral blood in female overweight & obese patients was significantly lower than that in underweight and normal weight patients. The percentage of eosinophil in peripheral blood of male overweight & obese patients was significantly lower than that of underweight and normal weight patients. Conclusions The overweight and obesity female CRSwNP patients were susceptible to be with comorbid asthma and recurrence after surgery, and controlling the weight of female patients with CRSwNP may prevent nasal polyps recurrence in the females.

Key words: sinusitis, body mass index, asthma, recurrence

CLC Number:

R765

Li Yan, Wang Qiqi, Zhang Yuling, Duan Su, Zhang Haibo, Wang Xiangdong, Lan Feng. Clinical characteristics of chronic rhinosinusitis with nasal polyps with different body mass index[J]. Journal of Capital Medical University, 2022, 43(6): 899-904.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2022.06.013

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2022/V43/I6/899

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