Journal of Capital Medical University ›› 2017, Vol. 38 ›› Issue (5): 671-676.doi: 10.3969/j.issn.1006-7795.2017.05.009

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Characteristic analysis of aeroallergens in Beijing patients suspicious of allergic rhinitis

Ma Siyuan1, Lou Hongfei1,2, Wang Chengshuo1,2, Zhang Luo1,2   

  1. 1. Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China;
    2. Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otorhinolaryngology, Beijing 100005, China
  • Received:2017-07-07 Online:2017-09-21 Published:2017-10-18
  • Supported by:
    This study was supported by National Natural Science Foundation of China (81630023, 81400444, 81470678), National Science Fund for the Major International Joint Research Program (81420108009), Beijing Municipal Administration of Hospitals' Mission Plan (SML20150203), Beijing Municipal Administration of Hospitals' Youth Programme (QML20150202), Beijing Clinical Research Foundation (Z141107002514122), Capital Health Development Fundation(2016-1-2052), Talents Project of Beijing Municipal Human Resources and Social Security Bureau (2016).

Abstract: Objective To analyze the characteristics of the main inhaled allergens in patients suspicious of allergic rhinitis (AR) with skin prick test,and provide reference for the management of AR. Methods Skin prick test was performed on patients with typical symptoms of allergic rhinitis in Beijing Tongren hospital from Jan. 1, 2011 to Jul. 31, 2013. The result of the test in different people was compared. Results 1Of the 2 598 patients, 2 292(88.2%) had positive result with clinical significance。2The most common four allergens in patients with allergic rhinitis were Dermatophagoides farina (43.1%), Dermatophagoides pteronyssinus (37.6%), Blaterlia Germanica (32.6%) and Mugwort (26.6%). Most of the patients were female, but there was no significant difference in the positive rate between the genders. 3Patients with single positive allergen (18.0%), dual positive allergens (22.6%) and triple positive allergens (19.4%) were the most common. The patients before adult had low positive rate in single positive allergen group.4 There were two peaks for the number of patients from April to June and from August to September respectively.5 In single positive allergen group, the Blaterlia Germanica has a much higher positive rate (31.6%). 6 The positive rates of dust mites varied in different age groups. Conclusion Dermatophagoides farina, Dermatophagoides pteronyssinus, Blaterlia Germanica and Mugwort are the most common four allergens in patients with allergic rhinitis, different age groups and months had different allergen distributions.

Key words: allergic rhinitis, allergen, epidemiology, skin prick test

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