Table of Content

15 January 1985, Volume 6 Issue 1

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论著

Role of Spinal Preparation in Identification of Spinal Projection Neurons

Lu Guowei

1985, 6(1):  1-8. 

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Effects of stimulating the cervicodorsal and dorsolaterai funiculi on transection and isolation preparations were compared in anesthetized and immobilized cats in terms of field potentials recorded from the lumbar enlargement with microelectrode.Similarly, typical field potentials were recorded from both the cervicodorsal and dorsolateral funiculi rostral and caudal to the dorsal column on transection preparation. On isolation preparation, however, typical fieldpotentials could be evoked only by stimulation of the dorsal columns caudal to the dorsal transection and smaller potentials by stimulation of the rostral end; whereas no detectable potentials could be recorded from stimulation of the dorsolateral funiculi rostral and caudal to the transection.The results show that the natural gap between spinal funiculi and the funicular transection itself are not sufficient to prevent the spread of stimulating current; this can effectively be done only by funicular dissection and the placement of an electrical barrier between the funiculi. It is thus supposed that electrical stimulatior on the transection preparation may lead to misidentification of spinal projection neurons; while isolation preparation can be used to effectively identify single and double spinal projection neurons.

The Projection of Spinocerebellar Neurons from the Sacrococcygeal Spinal Cord in the Cat. An Experimental Study Using Anterograde Transport of WGA-HRP and Degeneration

Xu Qunyuan;G. Grant

1985, 6(1):  9-17. 

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The projection from the sacrococcygeal cord to the cerebellum was studied by two kinds of techniques in the cat. In six cats WGA-HRP was injected caudal to a preceding unilateral cordotomy at the sacral level and the distribution of WGA-HRP labeled fibers and terminals was studied in the cerebellum In three additional cats degenerating fibers were examined by Fink-Heimer’s method after semi-transection of the lateral and ventral funiculi of the lowest lumbar cord. The WGA-HRP labeled mossy fiber terminals were located bilaterally in lobules Ⅰ-Ⅴ. Most of them were found in the anterior part of lobule Ⅱ. The terminals were concentrated in longitudinal zones parallel to the midplane. In lobule Ⅱ the terminals were most abundant in the superficial part of the folia. A few of terminals were observed, in addition, in sublobule ⅧB and the pars copularis of the paramedian lobuIe. Some terminals were also seen in the cerebellar nuclei. Labeled fibers were found unilaterally in the superior and inferior cerebellar peduncles, as well as in the spinal cord, rostral to the cordotomy, The results of the degeneration experiments were much the same as those of the WGA-HRp experiments.Present study indicates that there are several cell groups which send axons to the dorsal and ventral spinocerebellar tracts in the very lower spinal cord in the cat. Majority of these neurons relate functionally to cutaneous afferents from the distal hindlimb and tail.

Excitability Characteristics of the A-fibers in Peripheral Nerve of Mammal

Tao Yongxia

1985, 6(1):  18-28,8. 

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In this study we proved that, basing on a series of chronic and acute experiments, (1) it was not the fastest element of compound action potential that was recorded first during the course of gradual increment in intensity of the stimuli. When the common peroneal nerve trunk was stimulated by square pulse, it was the element of A_β that made its first appearence; (2) the negative square pulse with different parameters have the function of selectively exciting various A-fibers and (3) the compound action potential recorded was different, when the common peroneal nerve trunk was stimulated by the positive and negative square pulse with the same parameter.

Influence of Toxemia of Pregnancy on the Fetus and the Neonate

Zheng Guofen

1985, 6(1):  29-31,35. 

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60 autopsy cases of the fetus and the neonate, whose mother suffered from toxemia of pregnancy were analyzed in this paper. Influence of toxemia of pregnancy on the fetus and the neonate in regard to the intrauterine growth and the causes of death was studied.Intrauterine growth retardation (IUGR) was commonly seen in the fetus and the neonate, whose mother suffered from toxemia of pregnancy.Disturbances of blood circulation of the mother and anoxia, ischemia. infarction and premature separation of the placenta exert their influences on the intrauterine growth of the fetus and may lead to IUGR, intrauterine anoxia, prematurity of the newborn, fetal death and stillbirth.

论著

Observation on Hepatic Regeneration after Hepatectomy (Report of 6 Cases)

Guan Shinchun

1985, 6(1):  32-35. 

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Observation on 6 cases of hepatic regeneration after hepatectomy was reported. Liver scanning and liver function had been studied. Liver scanning showed that the regeneration of the liver was active about 6 months after hepatectomy and stopped about 2 years later. The liver function almost recovered within one month after operation. The method of clinical observation was discussed briefly.

Determination of the Guanine Plus Cytosine Content of Chlamydia Trachomatis DNA by Thermal Denaturation Temperature Method

Chen Cuizhen

1985, 6(1):  36-38,35. 

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Determination of the G+C content of DNA from strain TE55 chlamydia trachomatis by the thermal denaturation temperature (Tin) method which was improved by Lin Wang-ming, using the semiconductor thermistor thermometer was reported in this paper. This method is simple, convenient and can he repeated with satisfaction. The results showed that G+C content of strain TE55 C.trachomatis DNA was almost the same as those reported in literature. In future, this method can be used to identify and classify chlamydia in clinical samples.

Report of 16 Cases of Cerebellar Hereditary Ataxia-CT Scanning Analysis

Long Jie

1985, 6(1):  39-43,35. 

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16 patients with hereditary cerebellar atrophy were admitted to our hospital in the past three years. Computed tomography scans were performed on all of the patients. The CT scans in 2 cases were within normal limits,and The other 14 cases all showed remarkable cerebellar atrophy. The main positive findings were as following:1. The sulci of the cerebellar hemispheres and/or the vermis widened and could be seen clearly.2. The fourth ventricle was enlarged.3. The cisterns around, the cerebellum and brain stem such as the quadrigeminal, superior cerebella, cerebellopontine angle and the prepontine cisterns were enlarged.4 In some cases the cerebral atrophy could be demonstrated. Thus, CT scan can provide the objective evidence for the diagnosis and differential diagnosis of the disease.

论著

Clinical Observation on Rosacea Ophthalmopathy

Wu Zhijie

1985, 6(1):  43-45. 

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Ocular rosacea is a common complication of cutaneous rosacea. The clinical manifestations are presence of erythema, papules, pustules, hypertrophy of sebaceous gland and telengiectases in the skin, nose, cheeks, and forehead. It can lead to rhinophyma in the late stage.The eyes are characterized by the presence of chronic blephritis, meibomitis and diffuse hyperemic conjunctivitis. It can develop nodular conjunctivitis, episcleritis, keratitis, etc. if the course of disease exceeds two years.This paper reported 13 cases of ocular rosacea. Female was more affected than male, usually with bilateral involvement. The condition of disease was obstinate and relapse was commonly seen. It might lead eventually to visual impairment. After the use of antiinfective agents,corticosteroid, and excision of eonjunctiva around the focus, combined with vascular cautery, a definite therapeutic effect could be achieved.

Effect of Micromotion between Fracture Ends on Bone Healing

Li Zhifang

1985, 6(1):  46-48,52. 

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Models of humerus fracture were porformed in several rabbits, different methods of fixation were tried, and the bone healing on both fracture ends was observed.The result of the experiment disclosed that certain degree of micromotion could promote the bone healing. Absolute immobilizatio, on the contrary might slow down the healing. Discontinuity of fixation in the healing process might lead to the formation of false joint.The author believed that the relative stability and contact of the fractured ends were the elementary criteria for bone healing. The micromtion between the fracture ends favoured the bone healing.

论著

Osteologic Complication after Allotransplantion of Cadaver Kidney

Yu Huiyuan;Guan Delin

1985, 6(1):  49-52. 

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117 cadaver kidneys were transplanted to 97 patients from september, 1975 to February, 1981 in our hospital The transplanted kidneys in 28 patients functioned well in one year.After renal transplatation there appeared osteologic complication in four patients. Two patients suffered from vascular necrosis of the femoral or humeral head. compression fracture of the lumbar vertebrae was seen in one patient. Anothen one presented generalized osteoporosis with supported arthrodynia.we discussed the pathogenesis, clinical features and treatment of vascular necrosis in this paper.