Abstract: Objective To study the effects of Jianpi Xiaozhang supplement on electro-mechanical activity in rat.Methods Colophony globules were administered to rats by gastrogavage and the gastric emptying rate was calculated by counting the number of colophony globules in stomach. The movements of stomach before and after gastrogavage were recording by using high sensitive stress plate transducer.Results The gastric emptying rates in rats administered with Jianpi Xiaozhang supplement in the dose of (5 g/kg, 2 g/kg and 0.5 g/kg) were quicker than that in control group(P<0.001,P<0.001,P<0.05). Jianpi Xiaozhang supplement in the dose of (5 g/kg, 2 g/kg and 0.5 g/kg)increased markedly the average amplitude of gastric movement and gastric slow wave.Conclusion Jianpi Xiaozhang supplement dose-relatedly enhanced gastric electro-mechanical activity.

Key words: gastric electro-mechanical activity, Jianpi Xiaozhang supplement, gastric emptying rate, gastric movement