Table of Content

15 October 1986, Volume 7 Issue 4

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ABSTRACT OF ORIGINAL ARTICLES Histological and Immunohistochemical Changes of the Rat Thyroid Gland after Partial Hepatectomy

Li Lingfeng

1986, 7(4):  253-257,331. 

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The present study was designed to investigate the histological andimmunohistochemical changes of the thyroid follicular epithelial cells,during 1,2,3,7 and 14 days following partial hepatectomy.After thesham operation,the secretion activity of follicular epithelial cellsdeclined and were probably related to stress reaction.After largeportion hepatectomy,the follicular epithelial cells bccame heightenedapparently.Both the amount of colloid droplets and the immunoreactionsubstance of T₃,T₄,increased.2-3 days after operation,these changeswere most prominant;14 days later,such changes recovered graduallyto normal level.The above mentioned changes suggested that thesecretory activity of follicular epithelial cells increascd.After smallprotion hepatectomy,the changes of the follicular epithelial cells wereless marked.By analogy with the liver regenerative process,all thefindings suggested that the morphological and secretory activity changesof the follicular epithelia cells were closely related with liverregeneration.

Histochemicai Changes of Adrenal Cortex During Regeneration Following Partial Hepatectomy in Rats

Chin Shing;Sun Keji

1986, 7(4):  258-262,332. 

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1,3,6 days after partial hepatectomy,nine kinds of histochemicalreactions such as MAO,SDH,G6PD,LIPIDS,AIP,ATPase wereperformed on the rat adrenal cortex,Histochemical changes following partial hepatectomy were mainly located in the internal area of zonafaciculata and zona reticularis and were more intense than that followingsham operation,but the tendencies were similar.Changes 3 days afteroperation were the most obvious,especially the activities of SDH,G6PD,AIP,ATPase were increased.Lipids also had some variation.Such resultsdisclosed that the functional activity of internal area of zona faciculataand zona reticularis of adrenal cortex in rat enhanced after partialhepatectomy.These changes of adrenal cortex and the course of hepaticregeneration were parallel.

A Scanning Electron Microscopic Study on the Guangxi Strain of Plasmodium Inui in Late Sporogonic Stage

Ye Yiying

1986, 7(4):  262-264,332. 

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This paper reports a scanning electron microscopic observation on theGuangxi strain of plasmodium in late sporogonic stage in Anophelesdirus.The sporoblasts seemed to be irregular in shape or form branches,from which were budding the sporozoites.The early sporozoite buds werefinger-like and sometimes enlarged at the tip as a bulb.The nearlymature sporezoites were slender.In a few mature sporozoites a microporecould occasionally be found,which was located two-fifth of the lengh ofthe body from anterior end.As to the residual body of the sporoblast,some were spherical,but most were irregular in appearance,the surfacebeing a little coarse.

Preparation of α,α'-dithiobis [β-(2-furan)acrylic acid] and its Influence on the Serum Zinc Levels in Rats

Zhang Yinxia

1986, 7(4):  264-267,332,333. 

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In the present investigation,the preparation of α,α-dithiobis-[β-(2-furan)aerylic acid](DTFA)from furaldehyde and rhodanine and its effect on serum zinc concentration were studied in rats.By usingatomic absorption method serum zinc concentration was determined afteradministration of ZnSO₄ or mixture of ZnSO₄ and DTFA.It was shownthat the serum zinc level in rats after the administration of mixtureZnSO₄ and DTFA was much higher and long-lasting than that in ratfollowing a simple treatment with ZnSO₄.

Studies of the Effect of α,α'-dithiobis [β-2-furan)acrylic acid] on Binding of Zinc to HSA by Gel Chromatography

Zeng Zhaohui

1986, 7(4):  267-271,333. 

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In this paper,the effect of α,α′-dithiobis[β-(2-furan)acrylicacid](DTFA)on binding Zn to HSA by gel chromatography wasstudied.The amounts of HSA bound Zn,the molar ratio of Zn to DTFAand fluorescence spectrum of HSA were determind.It was found that:1.The DTFA could markedly increase the amount of HSA boundZn.In systems of HSA,Zn and DTFA the amount of Zn-HSA was 66.40%and the amount of Zn-HSA only 38.28% in the systems of Zn and HSA.The results obtained in the present investigation were consistent withthe animal experiment.2.The principal peak in the fluorescence spectrum of HSA was 345nm on excitation wave length 295 nm.Asimilarity in wave length of thefluorescence peak of HSA-Zn-DTFA systems was observed.Theseobservations suggestsd that mechanism of DTFA induced increase inserum zinc concentration involved the formation of a ternary complex ofAlbumin,Zinc and DTFA.

Effects of Ilexonin A and Nitroglycerin on Arachidonic Acid Metabolism

Sun Songsan

1986, 7(4):  271-275,334. 

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The inhibitory effect of ilexonin A(IA)on platelet aggregation in vitro and in vivo induced By adengsine diphosphate(ADP)whichactivates platelet function was studied in this paper.The effect of IA onprostacyclinlike substances was also investigated.Basing on in vivostudy,our result suggested that IA was an inhibitor of arachidonicacid(AA)which activated platelet function in another way.Meanwhile,IA inhibited the way by which ADP activated platelet function in vitroand in vivo.In further study with radioimmunassay,we measured theplasma levels of thromboxane B₂(TXB₂)and 6-keto-PGF₁ in rabbit.Theantithrombotic agent might be caused through the stimulation action ofIA of prostacyclin production from arterial endothelium in vivo.In vitroand in vivo experiments showed that nitroglycerin(NTG)had inhibitoryeffects both on ADP and AA.It also enhanced the inhibitory effect ofPGI₂-like substances on platelet aggregation.It was suggested that NTGexerted its regulating effect on TXA₂/PGI₂ balance.In the acutely lethalexperiment,both IA and NTG had apparent protective effects.

Studies on Toxicty of SF-Xiao Xi Ling

Jing Zhicheng

1986, 7(4):  275-278,334. 

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SF-Xiao Xi'Ling(Na₃PO₄·1/4NaOCl·12H₂O)has been identified forits disinfectant function by Cheng Du(The Municipal EpidemicPrevention Station and Beijing Municipal Centre of Hygiene and EpidemicControl).Experiments demonstrated that SF-Xiao Xi Ling could kill bothvirus and bacteria efficiently.We carried out the following studies,i.e.acute toxicity test,accumulative toxicity test and mutagenicassessment of SF-Xiao Xi Ling.The results showed that the LD₅₀valuewas 6937mg/kg B.W.by the oral route in mice.In rats,study on acuteoral toxicity revealed that the LD₅₀ was 6810mg/kg B.W.in female and5010mg/kg B.W.in male respectively.It belonged to basically untoxic.substance.The cumulation cofficient which was more than 12.8 disclosedits absence of any obvious accumulative effect.Micronucleus test of micebone marrow,testis chromosome aberration analysis in mice and Amestest were all negative.Mutagenicity wasn't discovered.We consider thatSF-Xiao Xi Ling is a promising disinfectant detergent,it can be usedfor cleaning and disinfecting fruits and utensils if the residualquantities are not too much.

Inflammatory Pseudotumors of the Lung:Clinical Analysis of 32 Cases

Ye Dangshi;Qiu Xinsun

1986, 7(4):  279-281,335. 

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In this paper 32 cases of inflammatory pseudotumors of the Lungare reported.They were sclerosing hemagioma in 17 cases,histiocytomain 14 cases and plasma cell granuloma in one.Before and duringoperation,the misdiagnosis rates were 93.8% and 87.5% respectively.The definite diagnosis rates in frozen section was 23.1%(3/13).25cases(78%)were misdiagnosed for more than 3 months,with the longestbeing 12 years.The causes of misdiagnosis,the diagnosis ofinflammatory pseudotumors of the lung,and the main points of thedifferential diagnosis to pulmonary tuberculoma,peripkeral type of lungcarcinoma,pulmonary hamartoma,adenoma and localized,mesotheliomaof pleura were disscused.

Aneurysms of the Aorta

Xiong Zhiquan

1986, 7(4):  282-286,335. 

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The data concerning aortic aneurysm from 92 autopsies weresummarized.These aneurysms classified by etiology were listed asfollows:Arteriosclerotic aortic aneurysm 65 cases,Dissecting aortic aneurysm 26 casesMycotic aortic aneurysm 1 caseAges at death ranged from 37 to 96 years and the average age was71.8 years.Rupture of aneurysm occurred in 52 cases(56.5%).Suddendeath occurred in 26 cases(28.3%).Forty-six cases died directly as aresult of acute hemorrhagic shock and acute pericandiac tampanadeseconcary to rupture of the aneurysm.The premortem diagnosis was madein 32 of 66 hospitalized cases(48.5%).In this paper,etiology,pathologicfeatures,complications and clinical manifestations of aortic aneurysmwere discussed.

Changes of Serum Copper and Zinc Conceatration in Patients With Hepatic Cancer

Yuan Zhenduo

1986, 7(4):  287-288,336,286. 

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Serum copper and zinc of 66 healthy adults and 17 patients with hepaticcancer were determined by atomic absorption spectrophotometry.Themean concentration of serum copper in healthy blood donors and volunteerswas 126.40±23.44μg/100ml(X±S.D),and zinc was 116.12±25.60μg/100ml.Theconcentration of serum copper was markedly increased in 17 patientswith hapatic cancer,in which the mean serum copper was 155.83±37.08μg/100ml(P<0.001).Whereas,serum zinc decreased in great degree(86.72±31.89μg/100ml,P<0.001).Serum Cu/Zn ratio increasedconspicuously(1.12±0.30→2.15+0.31,P<0.001).

Placenta Accreta—A Clinical and Pathological Analysis Of 20 Cases

Yang Zhenyun;Cao Dade

1986, 7(4):  289-291,336. 

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Placenta Accreta is an uncommon obstetrical complieation.20 Caseswere encountered in the Red-cross Chao Yang Hospital,Beijng,from1969 through 1984.The total number of deliveries were 49558 in the sameperiod.Most cases occurred between 37-42 getational weeks,only 2 casesat mid-term,Clinical menifestations were retention of placenta,fulledmanual removal of placenta and post-partum hemorrhage.Subtotalhystrectomies were performed on 17 cases.The remaining 3 cases weremanaged by manual removal of most part of the placental tissue withpreservation of uterus,Pronosis were favorable in all cases.