Hepatoprotective effects of dietary 5'-nucleotide on nonalcoholic liver injury in mice

doi:10.3969/j.issn.1006-7795.2016.03.021

Abstract

Abstract: Objective To investigate the hepatoprotection effects of dietary 5'-nucleotide in mice. Methods The 5'-nucleotide was administered by oral administration (40, 160, 640 mg/kg) for 30 days prior to acute carbon tetrachloride (CCl₄) hepatic damage in mice. Results Pretreatment with 5'-nucleotide effectively attenuated serum alanine aminotransferase (ALT) and improved pathological changes of the liver tissues in mice. Conclusion The 5'-nucleotide has potential hepatoprotective effects.

Key words: 5'-nucleotide, hepatoprotective effects, mice

CLC Number:

Gao Lifang, Luo Kui, Cui Shuxiang. Hepatoprotective effects of dietary 5'-nucleotide on nonalcoholic liver injury in mice[J]. Journal of Capital Medical University, 2016, 37(3): 356-359.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2016.03.021

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2016/V37/I3/356

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Hepatoprotective effects of dietary 5'-nucleotide on nonalcoholic liver injury in mice

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